We propose an in situ GISAXS experiment study in collaboration with Procter & Gamble UK (the partner of InnovaXN project), the world leading manufacturer in personal care products, to study the spontaneous self-assembly of novel polymer-surfactant multilayer films. Our ultimate goal is to use such complex coatings to provide long-lasting antimicrobial properties for surfaces, without the need for constant sanitization. The design of the system is based on the concept that such longevity in antimicrobial efficacy may be offered by creating a multilayer coating with antimicrobial agents uniformly dispersed through the whole film, which can be released over a sustained period of time. We will study the effect of film composition and external conditions, e.g. humidity, temperature and UV-irradiation, on the multi-layered structure in order to elucidate optimal composition for the sustained antimicrobial surface property.