To better understand the properties of lipid basednon-lamellar liquid crystalline nanoparticles, LCNP, as delivery vehicles or surface modifying systems, it is crucial to understand how they interact with and respond to different types of interfaces. Previous neutron reflectometry (NR) beam time on FIGARO, #9-13-331, provided us the opportunity to perform an initial study the adsorption of the GDO/POPC/P80 on hydrophilic silica surfaces, both pure silicon wafer and one cationic surface . The fitted data shows that the adsorbed layer consists of a very dense inner layer (of about 40 Å), where the compsosition of the layer depends on the surface characteristics and much less dense and very thick layer consisting of LCNP. Based on these results we now aim to reveal the mechanism of the interfacial process (attachment/spreading) by further kinetic studies of the layer formation using NR. We will also study how the particle composition affect composition of inner layer structure and how that affects the further attachment of LCNP.