C57BL/6 mice underwent 3 cycles of 1 week of WD (45% kcal from fat) exposure separated by 2 weeks of chow diet exposure (group CYCL) or stay under chow diet for 7 weeks (group CTRL). Food intake and body weight were monitored daily. In a first experiment, feces were collected 4 days before each reintroduction of the WD and the fecal microbiota composition was analyzed through 16S sequencing. In a second set of experiment, before the third cycle of WD of CYCL mice and in CTRL mice of the same age cecal samples were collected and the cecal microbiota composition was analyzed through 16S sequencing. Then, cecal samples from the CYCL and CTRL mice from a 3rd set of experiment were transplanted in naive mice to decipher whether differences in food intake behavior could be transmitted through the gut microbiota. Cecal microbiota of donor and recipient mice were collected and the microbiota composition was analyzed through 16S sequencing.