The python tool "Time dependent stress response seismicity model (TDSR)" is a modified effective Coulomb failure model to calculate earthquake rates as a function of stress loading and model parameter. The theory and examples are described in Dahm and Hainzl (2022): A Coulomb Stress response model for time-dependent earthquake forecasts, accepted in Journal of Geophysical Research, Solid Earth (doi xxxxxx). The TDSR toolbox is further developed under github at https://github.com/torstendahm/tdsr . A Sphinx generated code documentation and html pages are provided after installation. Examples published in Dahm and Hainzl (2022) are provided as code examples.