The adsorption of nanoparticles at interfaces has attracted strong interest in the last decade for its high scientific relevance, with applications covering very broad areas. However, despite the number of studies describing adsorption of NP at interfaces, a clear understanding of the rules governing nanoscale-wetting phenomena is still an open challenge mainly due to the lack of available techniques to characterize the nanoparticle-interface interaction. Very recently neutron reflectivity studies at air/water interfaces enabled us to determine unambiguously the immersion depth of such particles into the bulk aqueous phase, delivering invaluable information regarding their role in interfacial phenomena. This recent approach is, as far as we know, the only one that allows a complete characterization of the interaction of NPs, as small as a few nanometres and with a complex organic coating, with water-air interfaces. We now need to move from the idealised air/water interface to a real oil/water interface. We intend to use a combination of two known methodologies to probe oil/water interfaces to determine the distribution profile of NP at the hexadecane/water interface.