Replication Data for: "Parallel Cellular Metabolic Imaging by Merging MRI and Microfluidics for Personalised Medicine"

DOI

Experimental data used for the work “Parallel Cellular Metabolic Imaging by Merging MRI and Microfluidics for Personalised Medicine” (Title in works). In this work, we use hyperpolarised 13C nuclear magnetic resonance combined with MRI spectroscopic imaging to parallelise metabolic imaging. Here, we present the first platform for the task combining microfluidic devices. First, we validated the platform, extended the work to assess diverse experimental conditions and then test the differences between different cell types. Then, we used the platform to analyse the effect of commercially available drugs on HepG2, expand the platform to do sequential spectroscopy of different chip regions and finally prove that the platform can also be used with 3D cell models.

Identifier
DOI https://doi.org/10.34810/DATA3242
Metadata Access https://dataverse.csuc.cat/oai?verb=GetRecord&metadataPrefix=oai_datacite&identifier=doi:10.34810/DATA3242
Provenance
Creator Gomez-Cabeza, David (ORCID: 0009-0001-7287-065X); Mangas-Florencio, Lluís ORCID logo
Publisher CORA.Repositori de Dades de Recerca
Contributor Gómez Cabeza, David; Mangas Florencio, Lluis; Matajsz, Gergo; Marco Rius, Irene; Institut de Bioenginyeria de Catalunya
Publication Year 2026
Rights CC0 1.0; info:eu-repo/semantics/openAccess; http://creativecommons.org/publicdomain/zero/1.0
OpenAccess true
Contact Gómez Cabeza, David (Institute for Bioengineering of Catalonia); Mangas Florencio, Lluis (Institute for Bioengineering of Catalonia); Matajsz, Gergo (Institute for Bioengineering of Catalonia); Marco Rius, Irene (Institute for Bioengineering of Catalonia)
Representation
Resource Type Experimental data; Dataset
Format text/plain; text/x-pascal; image/png; image/svg+xml; application/zip; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet; application/octet-stream; text/csv; text/plain; charset=UTF-8; application/pdf; text/html; text/plain; charset=US-ASCII; image/vnd.dwg; application/vnd.ms-pki.stl; text/x-matlab; application/dicom; text/tab-separated-values
Size 2863; 1257; 26458; 115744; 25291; 114033; 30166; 116724; 30855; 118369; 27419; 92833; 9901; 24347; 9560; 23859; 9579; 24119; 9188; 23121; 23487; 38308; 24385; 52021; 27587; 52841; 212534130; 262114695; 262902242; 14761066; 130542651; 133785423; 16057661; 145350209; 154003073; 156144012; 13104377; 18532225; 132802331; 74128488; 15713259; 19105666; 18886757; 18881327; 12831; 68613269; 63953698; 62969942; 46282019; 46519895; 46562473; 64661772; 65863439; 61722119; 61022537; 61126794; 61038127; 35744596; 36752488; 34638576; 80000; 204800; 393216; 1428480; 1542; 24102; 88235; 23103; 97485; 21473; 77846; 23178; 85994; 27218; 91493; 7502; 20806; 7153; 20282; 7952; 21902; 7445; 20811; 7389; 20819; 2397; 1102; 28004; 50426; 29094; 58797; 1062; 24730; 95378; 23183; 94540; 21730; 92591; 19421; 64036; 20511; 92870; 24761; 97280; 21374; 94522; 24313; 95836; 21319; 93819; 6262; 18412; 5905; 18726; 5346; 17706; 5856; 17265; 6437; 18205; 14533; 70694; 15588; 21872; 684; 17797; 63715; 5871; 18857; 6159; 18485; 6995; 19499; 17890; 24132; 1157720; 2481933; 952613; 22592; 93063; 28540; 97786; 23561; 95507; 28794; 99947; 26163; 99423; 5548; 18385; 5883; 17220; 6212; 19182; 6383; 18524; 6504; 17835; 15660; 24171; 2261; 4126; 886075; 3872076; 3821316; 1589568; 14162; 14312; 12601; 13288; 13569; 13620; 12477; 14422; 13450; 13613; 13357; 13582; 12520; 12540; 14222; 13623; 13145; 12534; 13143; 13616; 12466; 12478; 12484; 14278; 13422; 12525; 14282; 14267; 12483; 13490; 14359; 14244; 12479; 13152; 14265; 14076; 14217; 13449; 12460; 12493; 12472; 13451; 12464; 13428; 13448; 596; 613; 597; 614; 612; 2474; 176380; 174055; 11633; 1035; 2849; 1110; 1093; 1097; 1660; 1677; 1125494; 28167; 61525; 14206; 2479035; 439815; 165474; 144831; 75584; 996438; 3290189; 588; 5981; 5982; 5502; 5519; 5964; 5965; 5116022; 81926; 206828; 206760; 206816; 206812; 206810; 206742; 206798; 206794; 133010; 133002; 133004; 132984; 81928; 206866; 82078; 81942; 82076; 206880; 81930; 81962; 81972; 206856; 206858; 206862; 206840; 206844; 206838; 133022; 133048; 133042; 81958; 81978; 14301; 14333; 953; 34825; 35763; 34369; 36835; 34806; 35341; 13936; 19107; 15215; 16956; 14860; 16806; 16028; 16063; 36124; 34775; 3426; 538; 556; 539; 555; 559; 160; 256; 208; 308; 479; 440; 752; 902; 21722; 19297; 18817; 18841; 21654; 23275; 21150; 19289; 23807; 18825; 19359; 21432; 19859; 19358; 19298; 21737; 22197; 23099; 23323; 21409; 21433; 23808; 21739; 22205; 19367; 18838; 22203; 18842; 21848; 19867; 23821; 23550; 19855; 21439; 23327; 22206; 18826; 18859; 23812; 18863; 23328; 825; 914; 870; 781; 824; 780; 3003; 30733; 31920; 26989; 2903; 3121; 3021; 3004; 27006; 31903; 5724; 17403; 2886; 17622; 6192; 6256; 3020; 1450; 1029; 301177; 160086; 140117; 32484; 165107; 384259; 156505; 53984; 41797; 39039; 37152; 38928; 37041; 43990; 289; 455; 430; 705; 888; 4731; 311; 481; 447; 760; 903; 673; 759; 310016; 288000; 737280; 768000; 614400; 120960; 11887; 12015; 11581; 11993; 12057; 12017; 11696; 12014; 11953; 11459; 11677; 11745; 11749; 12173; 11743; 11754; 11687; 12067; 12069; 11744; 12002; 11997; 11683; 12068; 11955; 12170; 12108; 12065; 11644; 11983; 11585; 11686; 11750; 11693; 12107; 11458; 11457; 11992; 12054; 12097; 11643; 540; 557; 952; 586; 569; 944; 962; 818; 934; 835; 179284; 179099; 179315; 179036; 178956; 178901; 8482; 179758; 179825; 179132; 179297; 179363; 180081; 179862; 178839; 8901; 179135; 179256; 179424; 180068; 179281; 179078; 178997; 178675; 5978; 13431; 773604; 1887; 1904; 1654; 1688; 340275; 157674; 140875; 12884; 809053; 6937; 7028; 6936; 7053; 6907; 6993; 7125; 7056; 7062; 6934; 7112; 7012; 7344; 7045; 7390; 7013; 6919; 7129; 3519; 6905; 6901; 7377; 6932; 6908; 6904; 7030; 7408; 7128; 6906; 6933; 6935; 6912; 7040; 7014; 7042; 7393; 7059; 7407; 7036; 1282; 885
Version 1.0
Discipline Life Sciences; Medicine