Data related to the publication "Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading", Parmenter et al., 2024, https://www.biorxiv.org/content/10.1101/2024.08.19.608559v2Full methodology described in the above publication.Total data size = 41 GBData used for statistical analysis:sCT_DVC_stats_data.csv : Data used for statistical analysis shown in Fig. 3 and Fig. 4DIAD_stats_data.csv : Data used for statistical analysis shown in Fig. 6WAXD processing code:processing_folder_D-period.py : python code for measuring diffraction peak parametersctMapperGUI.py : python code for mapping WAXD parameters onto X-ray projection imageExample sCT and DVC dataset (sample 5):162365_2560xy_2160z_pag100_us2p5_8bit.tif : reconstructed sCT image of sample under 1 N preload, 13 GB, recommend opening in imageJ162366_2560xy_2160z_pag100_us2p5_8bit.tif : reconstructed sCT image of sample after 40 micron displacement, 13 GB, recommend opening in imageJ162365_caudal_mindist4p5_mesh.inp : mesh of caudal VEP used for creating the DVC pointcloud, ABAQUS input file162366_cranial_mindist4p5_mesh.inp : mesh of cranial VEP used for creating the DVC pointcloud, ABAQUS input file162365_caudal_pointcloud.txt : caudal VEP pointcloud for DVC162365_cranial_pointcloud.txt : cranial VEP pointcloud for DVCdvc_162365_caudal.disp : DVC displacement results for caudal VEP, output from iDVC executable, can visualise in Matlabdvc_162365_cranial.disp : DVC displacement results for cranial VEP, output from iDVC executable, can visualise in Matlabdvc_162365_caudal_1-sw25.Lstr.csv : strain data for caudal endplate generated from disp filesample5_caudal_step1.csv : strain data for caudal endplatesample5_caudal_step1.csv : strain data for cranial endplate generated from disp filesample5_force_readout.xlsx : force, displacement, time data readout from the mechanical testing rig during the experimentsample5BinaryROIs.zip : binary images of regions used for microarchitecture analysissample5ROImsvalues.xlsx : microarchitecture values for regions of interestExample correlative sCT and WAXD dataset (sample 16):17565_2560xy_2160z_us1_8bit.tif : reconstructed sCT image, 13 GB, recommend opening in imageJ17565_BinaryROI_tifs : binary image regions used for microarchitecture analysis17567 002 dperiod map.png : 002 d-period mapped on X-ray projection17567 002 width map.png : 002 peak width mapped on X-ray projection17567_310_Peak_D-period_data.txt : 310 d-period for each beampath through the sample17567_310_Peak_width_data.txt : 310 peak width for each beampath through the sample17567_D-period_data_002.txt : 002 d-period for each beampath through the sample17567_Width_data_002.txt : 002 peak width for each beampath through the samplek11-17567.nxs : raw diffraction data (part 1), recommend opening in DAWN (both parts required)k11-17567.zip : raw diffraction data (part 2), recommend opening in DAWN (both parts required)k11-17567_processed_220722_184414.nxs : processed diffraction data, recommend opening in DAWN