Craniopharyngiomas are neoplasms of the sellar and parasellar region which develop from the epithelium of the primordial craniopharyngeal canal (Rathke's pouch). Despite their WHO classification as type 1 tumours, craniopharyngiomas are associated with multiple comorbidities including hypopituitarism, obesity and somnolence

In this clinical study, we investigated the management and outcomes of a large cohort of patients with craniopharyngioma, both childhood and adult-onset, from three tertiary endocrine centres in the United Kingdom. The primary aim of this study was to examine temporal trends in the management of craniopharyngioma and their impact on long-term patient’s endocrine function.