This dataset includes the data for two heat pump systems installed in the hotels in Italy within the project MultiPACK.The heat pump is installed in a hotel located in a tourist area in North Italy. It is intended to provide heating, cooling and hot water to a hotel, which is open nearly all over the year.The unit can benefit from groundwater as the heat source or heat sink. The heat pump features a two-phase multi ejector as an expansion device, able to utilise expansion work. An original two-evaporator layout is implemented, where the first one is gravity driven and the second one is ejector driven.