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Interactions of native vs. modified protamines with Gram-negative model biome...
Protamines are cationic antimicrobial peptides found commonly in the sperm cells of fish such as herring and salmon that are particularly active against food-borne Gram-negative... -
Joint Diamond/ISIS proposal 22078
The basis of a biological cell membrane is a lipid bilayer containing functional proteins. Its purpose is to form a selective barrier that separates the aqueous fluids inside... -
Using neutron reflectivity from monolayer models of bacterial cell membranes ...
Antimicrobial peptides are being investigated as an alternative to antibiotics, as bacteria seem less able to acquire resistance to them. We have been investigating the way in... -
Incorporation of PAN-pyrene swollen micelles in crosslinked polyelectrolyte f...
We have been studying the formation of solid polymer-surfactant films at the air-solution interface formed from cationic surfactants with PEI. We wish to use the micelles... -
Realistic bacterial membrane mimetics to understand antimicrobial activity & ...
We will use neutron reflectivity measurements of lipopolysaccharide (LPS) layers at the air-water interface to help develop a realistic mimetic for the periphery of bacteria... -
Head Group charging and anaesthetic Interaction with Model Bilayers
The mechanism of general anaesthetic action is poorly understood despite their widespread use. It is hoped that investigating the interaction of anaesthetics with lipid bilayers... -
Using SERGIS to characterise monolayer buckling on the approach to collapse
Thin films just one or a few molecules thick can play an important role in controlling many important phenomena. This includes the lipid monolayers that coat the surface of our...
