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Novel computational approaches to study CRC tumour microenvironment organoids...
Poster for the 2021 CRUK Cancer Evolution Symposium. Colorectal cancer (CRC) tumours present as a heterocellular setting where the colon epithelia harbouring oncogenic... -
Stromal and Oncogenic Regulation of Colonic Stem Cells Revealed by Single-cel...
Poster presented at the 2022 UCL Cancer Domain Symposium. Awarded with the First Prize Runner-up. -
Impact of treatment history on drug resistance of metastatic colorectal cance...
Background Treatment of metastatic colorectal cancer (mCRC) is impeded by the development of drug resistance. To increase treatment efficacy, we need to understand how exposure... -
Quantification of verapamil metabolites in patient-specific hepatocyte organo...
The objective of the experiment was to compare the efficiency of drug metabolism in patient-specific hepatocyte organoids (h-HepOrg), periportal liver assembloids (Assmbl) and...
