9 datasets found

Here, we provide an improved version of the PN40024 genome assembly, called PN40024.v4, which combines the top-quality Sanger contigs from the 12X version with Pacific...

The aim of the present work is to gain an understanding of the interaction of DNA with the phospholipid bilayers. The effect of different forms of DNA, the presence of divalent...

Bio-responsive polymers hold great promise as delivery vehicles for drugs, peptides and proteins as their chemistry can be tuned to effect a change in physico-chemical...

Gene delivery vehicles, known as LPD complexes, prepared from mixing cationic lipid vesicles (L) with cationic peptide (P) and DNA (D) have proven to be very effective at...

These experiments are part of a much broader programme at the University of Reading. focused on the use of water-soluble half-acetylated chitosan as a mucoadhesive polymer,...

Complexes prepared from cationic, dichain lipid (L) vesicles, positively chargely targeting peptides (P) and negatively charged DNA (D) or siRNA (R), known as LPDs and LPRs...

To date complexes prepared from vesicles composed of dichain, cationic lipids (L) with negatively charged DNA (D), known as LD complexes have emerged as one of the major...

We propose to make neutron reflectivity measurements of hydrophillic polymers covalently attached, via thiol chemistry, to the gold-water interface. In particular, we will...

We have recently developed novel ternary lipopolyplex vectors (i.e. gene delivery vectors containing cationic lipid, plasmid DNA and a cationic peptide) in which, for the first...