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The evolution, evolvability, and engineering of gene regulatory DNA [GPRA]
In order to generate data produce a generalizable sequence-to-expression model, we randomly sampled ~21 million 80 bp sequences and tested their activity as promoters (in yeast)... -
The evolution, evolvability, and engineering of gene regulatory DNA [RNA-seq]
Here, we used RNA-seq to quantify expression conservation across many Ascomycete yeasts. Overall design: We used strand-specific RNA-seq (dUTP) to quantify mRNA expression in... -
Replication Data for: Low interspecific variation and no phylogenetic signal ...
The dataset contains the code and data necessary for repeating the analyses found in the paper. The data contains 1822 narrow-sense heritability (h2) and 378 coefficients of...