19 datasets found

We have recently developed novel ternary lipopolyplex vectors (i.e. gene delivery vectors containing cationic lipid, plasmid DNA and a cationic peptide) in which, for the first...

To date complexes prepared from vesicles composed of dichain, cationic lipids (L) with negatively charged DNA (D), known as LD complexes have emerged as one of the major...

Complexes prepared from cationic, dichain lipid (L) vesicles, positively chargely targeting peptides (P) and negatively charged DNA (D) or siRNA (R), known as LPDs and LPRs...

The aim of the proposal is to improve understanding about combinations of normal surfactants and hydrotropes. The systems of study are reference oil-water interfaces, provided...

Surprisingly little work has been done to gain understanding about the nature, stability and properties of nanoparticles dispersed in organic solvents (organosols). Recently...

Recent results show that gold nanoparticles (Au-NPs) can be included into microgels (MGs). UV-visible spectra (Figure 1) suggest the original Au-NP sols retain their size and...

New types of water-in-CO2 microemulsions using mixed surfactant systems will be investigated by high-pressure SANS (HP-SANS). Exciting new results (see report on RB820030) have...

Gene delivery vehicles, known as LPD complexes, prepared from mixing cationic lipid vesicles (L) with cationic peptide (P) and DNA (D) have proven to be very effective at...

There is a well-documented track record of research into water-in-CO2 (w/c) microemulsions. Using newly discovered CO2 compatible surfactants, the next step is to explore...

The aim of this proposal is to investigate a novel approach to phase separation in microemulsions using careful choice of organic solvents, and appropriate mixtures....

This proposal aims to explore organogel systems, like those recently decsribed1-3, but made from new CO2 philic surfactant-gelators. These have been synthesised to feature...

This proposal concerns a novel approach to phase separation in self-assembling colloidal systems. Microemulsions can be readily formulated to display critical-type phase...

Complexes prepared from cationic, dichain lipid (L) vesicles and negatively charged siRNA (R), with and without positively chargely targeting peptides (P) known as LR or LPR...

The proposal aims to explore different self-assembly structures in CO2 with the focus of developing viscosity modifiers for supercritical CO2 (sc-CO2). This is part of a...

The aim of this experiment is to investigate surfactant aggregation in ionic liquids and also ionic liquid ¿ oil and ionic liquid ¿ water microemulsions via SANS. Contrast...

The proposal aims to explore water-in-CO2 (w/c) microemulsions with new, very promising hydrocarbon surfactants. The compounds are generated using standard chemistry1 but with...

There is exciting potential for SANS to resolve an important problem in homogeneous catalyst chemistry. The Pd-chiral catalyst 1+ below has significant pan-industrial potential...

This research project addresses an overlooked, but fundamental issue of colloid science: surfactant adsorption dynamics at nanoparticle-organosolvent interfaces. Adsorption of...

The aim of the present study is to the determine, using specular neutron reflection (SNR), the structure of layers formed by novel tri-chain cationic lipids in combination with...