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Chromatin reorganization as a major factor in the control of nuclear stiffness
DNA organization on chromatin has been largely studied for its consequences in gene expression, but its contribution to the cell mechanics is often neglected despite the nucleus... -
MeCP2 heterochromatin organization is modulated by arginine methylation and s...
Rett syndrome is a human intellectual disability disorder that is associated with mutations in the X-linked MECP2 gene. The epigenetic reader MeCP2 binds to methylated cytosines... -
MeCP2-induced heterochromatin organization is driven by oligomerization-based...
Heterochromatin is the highly compacted form of chromatin with various condensation levels hallmarked by high DNA methylation. MeCP2 is mostly known as a DNA methylation reader...
