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Reconstructing the gene regulatory network that shaped the evolution of larva...
Cnidarians are the only non-bilaterian group to evolve ciliated larvae with an apical sensory organ integrated with neurons, possibly homologous to the bilaterians. Within... -
The evolution of DNA methylation inheritance and programming in animals
DNA methylation has been found throughout animal kingdom, but it is still unclear whether this epigenetic mechanism affects the evolution of genomic elements in animals. Here,... -
An ancestral Wnt-Brachyury feedback loop and vertebrate-specific recruitment ...
Transcription factor brachyury plays a key role during mesoderm development in vertebrates. In this study we study study the effect of this transcription factor in diploblastic... -
Antibiotic treatment influences cnidarian regeneration rate
THis project aims to profile microbial communities using metabarcoding of the V4 region of the 16S rRNA of cninadarians (Nematostella vectensis (non-symbiotic) and Exaiptasia... -
Chromatin loops are an ancestral hallmark of the animal regulatory genome [Mi...
We characterised the genome organization in non-bilaterian animals (sponge Ephydatia muelleri, ctenophores Mnemiopsis leidyi and Hormiphora californensis, placozoans Trichoplax... -
Genome-wide evolutionary analysis of eukaryotic DNA methylation
Eukaryotic cytosine methylation represses transposable elements, but also occurs in bodies of active genes. The extent to which these processes are conserved is unclear, and... -
The role of DNA methylation in genome defence in Cnidaria and other invertebr...
Considerable attention has recently been focussed on the potential involvement of DNA methylation in regulating gene expression in cnidarians. Much of this work has been centred... -
Tracking the origin and evolutionary dynamics of RNA editing in metazoans
Whole-genome DNA-seq and strand-specific RNA-seq on 18 species, including 14 metazoans and four unicellular eukaryotes closely related to metazoans. For each species, two to... -
Edwardsiid Genomes
There is currently little information about the evolution of gene clusters, genome architectures and karyotypes in early branching animals. Slowly evolving anthozoan cnidarians... -
Seawater carbonate chemistry and reproduction and offspring performance of Ne...
Ocean acidification (OA) resulting from anthropogenic CO2 emissions is impairing the reproduction of marine organisms. While parental exposure to OA can protect offspring via...
