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Unravelling the thermal denaturation and stability of the solution structures...
The glycosylation of glycoproteins is a major determinant of their stability, and glycans also affect their aggregatibility (precipitation). An understanding of this is... -
Protein interactions at solid-liquid interfaces: The effect of affinity colum...
Biopharmaceuticals are manufactured using chromatographic procedures including adsorption and desorption processes at the solid-liquid interface. These events take place in... -
Solution structures of the immunologically important proteins IgG and C3b
IgG antibody represents one-third of new drugs currently in development. We will unravel the solution structures of the Fab and Fc fragments within IgG. Following our earlier...