23 datasets found

We report analyses of the types, amounts and stage-dependence of microRNAsfound in D. immitis culture media recovered after incubating 800,000 microfilariae for 6 days, 500...

Comparative transcriptomic analysis of adult females and males of the Dirofilaria immitis Kentucky isolate and JYD-34 isolate, with specific emphasis on the constitutive...

D. immitisrofilaria immitis, or canine heartworm, is a filarial nematode parasite that infects dogs and other mammals worldwide. Current disease control relies on regular...

This study focuses on validating 4 SNP markers using the Droplet-digital PCR, which was previously validated using clinical samples on a MiSeq sequencing platform.

Mosquito-borne helminth infections are responsible for a significant worldwide disease burden in both humans and animals. Accordingly, development of novel strategies to reduce...

Recent evidence has confirmed the development of ML-resistant isolates in the US which are genetically distinct from wild-type populations. Previous research clinically...

This study utilised phenotypic and genotypic assays to determine the presence of macrocyclic lactone resistant Dirofilaria immitis in Australia. We surveyed dogs from Queensland...

For the past 30 years, chemoprophylaxis with macrocyclic lactone (ML) endectocides has been the primary strategy for canine heartworm (Dirofilaria immitis) control in both the...

For many parasitic nematode species, adults inhabit the GI tract and eggs are shed in faeces and subsequently develop through larval stages in the faeces or soil before...

Dirofilaria immitis is a filarial parasite of dogs. The genome sequencing project was undertaken in collaboration between the GenePool, University of Edinburgh, and the...

This study has provided novel insights into the transcriptome of D. immitis which sheds light on extensive investigations of biological molecular processes and the mechanisms of...

RNA from different Dirofilaria immitis sexes and stages were sequenced to identify isoforms and correct predicted gene models

This study examined two cases of asymptomatic canine heartworm (Dirofilaria immitis) disease in dogs from Townsville, Australia. These dogs reportedly received 'rigorous'...

This study involved whole genome amplification and whole-genome sequencing of single Dirofilaria immitis microfilariae samples isolated from dog blood. Accessing these immature...

Here, we compared ribosomal depletion methods in Brugia malayi (B. malayi) containing the symbiotic endosymbiont Wolbachia. We sequenced total RNA, Terminator exonuclease...

We cultured D. immitis L3 and L4 of two laboratorial strains with different susceptibility status to macrocyclic lactone drugs in vitro. Excretory/secretory microRNAs were...

Transcription profile of Dirofilaria immitis adult male and female worms using Illumina Solexa GAIIx RNASeq paired end reads

To understand how microRNA are involved in the complex biology of this zoonotic parasite, we describe our initial attempts to characterize small RNA in adult Dirofilaria immitis...

Provided a new genomic assembly for five different strains of Dirofilaria immitis (heartworm)

This study aimed to determine whether multiplex qPCR targeting Dirofilaria immitis and Wolbachia DNA can be a substitute for the quantitative Modified Knott's test. To do so,...