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Effect of serum on the structure of gene delivery vehicles
To date complexes prepared from vesicles composed of dichain, cationic lipids (L) with negatively charged DNA (D), known as LD complexes have emerged as one of the major... -
Probing the kinetics of the formation of lipid, peptide and DNA/siRNA complex...
Complexes prepared from cationic, dichain lipid (L) vesicles, positively chargely targeting peptides (P) and negatively charged DNA (D) or siRNA (R), known as LPDs and LPRs... -
Effect of reversing lipid head group charge on vesicular properties
Zwitterionic lipids such as phosphatidylcholine (PC) are major components of the membranes that compartmentalize organisms. Although there is a large literature on PC, cationic... -
Structure of siRNA containing delivery vehicles: effect of serum
Complexes prepared from cationic, dichain lipid (L) vesicles and negatively charged siRNA (R), with and without positively chargely targeting peptides (P) known as LR or LPR...