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Deep enzymology data related to Adam et al.: DNA sequence-dependent activity ...
Methylation of long hemimethylated DNA substrates: Methylation of the 349 bp long hemimethylated substrate with DNMT1 was carried out in 1X methylation buffer (100 mM HEPES, 1... -
Deep enzymology data related to Adam et al.: DNA sequence-dependent activity ...
Methylation of random flank substrates: Libraries of double stranded DNA substrates with unmethylated or hemimethylated CpG sites in randomized sequence context were methlyated... -
NGS data related to Adam et al.: On the accuracy of the epigenetic copy machi...
Expression and purification of DNMT1 for biochemical work Full length murine DNMT1 (UniProtKB P13864) was overexpressed and purified as described (Adam, et al. 2020) using the...