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A neutron study of capability of aggregation of the Abeta1-40, Abeta1-42 and ...
The aim of the proposed SANS experiment is to study the capability of aggregation, the shape and the size of aggregates of three amyloid peptides named (Abeta1-40, Abeta1-42 and... -
Novel protophane and cyclophane surfactants
Novel Gemini surfactants (protophanes and cyclophanes) have been synthesised as model biological anion receptors, and their critical micelle concentrations determined by surface... -
Is there a CMC for surfactants in non-aqueous solvents?
The aim of this project is to use SANS to determine if a critical micelle concentration (CMC) exists for the formation of inverse micelles in non-polar solvents. The CMC is a... -
Are hydrotropes a unique class of solutes?
The aim is to improve understanding of solution properties and aggregation of hydrotropes and alkyl¿hydrotropes, and the relationship with common surfactants. Although they are... -
Assessing a potential method to form kinetically trapped, self-assembling nan...
Cyclic peptide-polymer conjugates can readily self-assembly into long nanotubes, and are being extensively studied for drug delivery applications. Recently, using SANS and... -
Controlling the length of polymeric supramolecular nanotubes
The self-assembly of (cyclic peptide)-polymer conjugates provide a versatile and functional platform for the precise design of polymeric supramolecular nanotubes. Moving the... -
Co-micellization of hydrotropes and surfactants
This proposal builds on recent work with hydrotropes alone (Langmuir, 2011, 27, 12346-12353); now co-micellisation of hydrotropes with surfactants will be investigated. The aim... -
The structure of nanographene and nanographite intercalates in solution
We aim use SANS to study in situ structure of solutions of uncharged and charged graphene formed by dissolving graphite and graphite intercalation compounds. We wish to compare... -
The effect of polymer therapeutics on the structure of mucin solutions toward...
Progress in the development of nano-sized hybrid therapeutics and nano-sized drug delivery systems - "nanomedicines" - over the last decade has been remarkable. One key...
