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Biochemically diverse CRISPR-Cas9 orthologs
CRISPR-Cas9 nucleases are abundant in microbes. To explore this largely uncharacterized diversity, we applied cell-free biochemical screens to rapidly assess the protospacer... -
Clinical metagenomics and metatranscriptomics for pathogen discovery
This project aims to develop DNA and RNA sequencing as tools for pathogen discovery in a clinical setting.