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Transcriptomes of ascidian embryos injected with antisense morpholino oligonu...
To identify genes regulated by Tbx15/1822, transcriptomes of ascidian embryos injected with antisense morpholino oligonucleotides against Tbx15/18/22 were analyzed. -
Ciona robusta SELEX-seq dataset
This project's aim was to describe the in vitro binding specificity of transcription factor DNA-binding domains from the ascidian Ciona robusta, using a high throughput... -
Brachyury controls Ciona notochord fate as part of a feedforward network [I]
The notochord is a defining feature of the chordates. The transcription factor Brachyury (Bra) is a key regulator of notochord fate but here we show that it is not a unitary... -
Brachyury controls Ciona notochord fate as part of a feedforward network [III]
The notochord is a defining feature of the chordates. The transcription factor Brachyury (Bra) is a key regulator of notochord fate but here we show that it is not a unitary... -
A microRNA-mRNA Expression Network during Oral Siphon Regeneration in Ciona [...
Among the Chordates tunicates demonstrate the highest capacity for regeneration, ranging from full-body regeneration in colonial ascidians to appendage regeneration in solitary... -
A single cell transcriptional roadmap for cardiopharyngeal fate diversificati...
Dynamic gene expression programs determine multipotent cell states and fate choices during development. Multipotent progenitors for cardiomyocytes and branchiomeric head muscles... -
Single-cell transcriptome profiling of the Ciona larval brain
The tadpole-type larva of Ciona has emerged as an intriguing model system for the study of neurodevelopment. The Ciona intestinalis connectome has been recently mapped,... -
10X Genomics Single Cell RNAseq of wild-type Ciona robusta embryos at 12 hour...
We used 10X Genomics Chromium system to profile single cells from a pool of Wild-type Ciona robusta embyros at 12 hours post fertilization (hpf) Overall design: A few hundred... -
Quantitative proteome dynamics across embryogenesis in a model chordate
The evolution of gene expression programs underlying the development of vertebrates remains poorly characterized. Here, we present a comprehensive proteome atlas of the model... -
The uncharacterized gene Rnf149 is a regulator of cardiopharyngeal development
To assay Rnf149 function during early cardiopharyngeal specification, bulk RNAseq was performed to profile the FACS-purified cardiopharyngeal lineage cells isolated from20 hpf... -
Ciona intestinalis, Ciona roulei, and Ciona robusta raw sequence reads from d...
Double-digest restriction-site associated DNA sequences (PstI-MseI) for the marine tunicate species Ciona intestinalis, C. roulei and C. robusta. -
HT-SELEX dataset of Ciona robusta transcription factors
Transcription factors (TFs) control gene transcription, binding to specific DNA motifs located in cis-regulatory elements across the genome. The identification of TF binding... -
ascidian larval transcriptome
RNA-seq data of papillae and body in larval ascidian -
A microRNA-mRNA Expression Network during Oral Siphon Regeneration in Ciona [...
Among the Chordates tunicates demonstrate the highest capacity for regeneration, ranging from full-body regeneration in colonial ascidians to appendage regeneration in solitary... -
The reconstruction of invasion histories with genomic data in light of differ...
Unravelling the history and pathways of range-shifting species is key for understanding their past, current, and future distributions. Anthropogenic transport of species alters... -
Single-cell analysis of cell fate bifurcation in the chordate Ciona
Inductive signaling interactions between different cell types are a major mechanism for the further diversification of embryonic cell fates. Most blastomeres in the model... -
Ciona robusta Islet overexpression and CRISPR (in papillae) bulk RNAseq
We wished to identify transcriptional targets of Islet in the papillae of Ciona robusta at 12 hpf, so Islet was overexpressed (FoxC>Islet) in addition to knocking out Islet... -
Brachyury controls Ciona notochord fate as part of a feedforward network [IV]
The notochord is a defining feature of the chordates. The transcription factor Brachyury (Bra) is a key regulator of notochord fate but here we show that it is not a unitary... -
Sinus venosus adaptation models prolonged cardiovascular disease and reveals ...
How two-chambered hearts in basal vertebrates have evolved from single-chamber hearts found in ancestral chordates remains unclear. Here, we show that the teleost sinus venosus... -
Single-cell RNA-seq profiling of early embryonic development in Ciona Robusta
During development, stem and progenitor cells divide and transition through germ layer- and lineage-specific multipotent states to generate the diverse cell types that compose...