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20Mammals
Definition of functional regulatory regions in the vast non-coding fractions of mammalian genomes remains a daunting challenge that underscores our limited understanding of... -
Comparative analysis of genome-scale, base-resolution DNA methylation profile...
We mapped DNA methylation in 580 animal species (535 vertebrates, 45 invertebrates), resulting in 2443 genome-scale, base-resolution DNA methylation profiles of primary tissue... -
RNA-Seq analysis of gene expression divergence in mammalian liver
The connection between evolution of regulatory elements and downstream gene expression is incompletely understood in mammals. We carried out a large-scale comparison of matched... -
G10K_VGP_Transcriptome_Sequencing
The Vertebrate Genomes Project aims to provide annotated reference genome sequences for all vertebrate species. This project contains transcriptome data from various sequencing... -
Genome Skimming with Nanopore Sequencing Precisely Determines Global and Tran...
This study determines that genome skimming, shallow depth of sequencing, is capable of accurately quantifying global DNA methylation level across a range of vertebrates. -
Mitochondrial heteroplasmy in vertebrates using ChIP-sequencing data
Mitochondrial heteroplasmy, the presence of more than one mtDNA variant in a cell or individual is not as uncommon as previously thought. It is mostly due to the high mutation...