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Structural examination of self-assembled floating membranes below grafted lip...
Robust, reliable, and protein-free bacterial membrane mimicking systems compatible with the high through put screening techniques will largely facilitate the discovery of new... -
Interaction of an antimicrobial peptide from Lactobacillus gasseri supernatan...
A short peptide, composed of 12 amino acids (EFVFVAHAVPVM), presenting a strongly hydrophobic character, was recently isolated from Lactobacillus gasseri supernatant (AMP12).... -
The impact of synthetic perfumes on surfactant self-assembly.
This proposal is part of a broad collaboration between Oxford, CCLRC, and Unilever in the study of surfactants and mixed surfactants at interfaces and in solution. This is an... -
Structure of the interaction between complement factor H (CFH) and complement...
Complement comprises key proteins in innate immunity that forms a major defence and clearance system in blood. CFH is the major regulator of active C3b formed from C3. C3d is a... -
Understanding Surfactant-Semiconducting Polymer Interactions for Optimisation...
This dataset has no description
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Comparative Interaction Studies of Antimicrobial Agents on Bacterial Membrane...
The outer membrane (OM) of Gram-Negative bacteria (GNB) is an asymmetric structure which contains complex lipids known as lipopolysaccharides (LPSs) on the outer surface. LPSs... -
Optimisation of Experimental Conditions for the Study of Anionic Self-Assembl...
We have developed a Self-assembled floating supported membrane sample system comprised of unsaturated phospholipid bilayers held ~1nm from a PEGylated charged alkane thiol SAM... -
Comparative Interaction Studies of Antimicrobial Agents on Bacterial Membrane...
The outer membrane (OM) of Gram-Negative bacteria (GNB) is an asymmetric structure which contains complex lipids known as lipopolysaccharides (LPSs) on the outer surface. LPSs... -
Self-assembly in biosurfactants and biosurfactant / surfactant mixtures
This proposal is part of a new project which is a collaboration between Oxford, Newcastle, Ulster, and Unilever on the development of sustainable laundry detergents, using... -
A complex model of the bacterial outer membrane containing oriented proteins ...
The Outer Membrane (OM) is found in bacteria which cause plague, cholera & Legionnaire¿s disease. It is important as; a barrier to antibiotics & the site of... -
Neutron Reflectivity Study of Antimicrobial Peptides Interacting with Lipopol...
The outer membrane (OM) of gram negative bacteria is mainly constituted of highly polydisperse and amphiphilic lipopolysaccharide (LPS), an endotoxin which is accompanied by... -
Orientation of an Antimicrobial Peptide in Eukaryotic and Prokaryotic Membranes.
Antimicrobial peptides are small, usually alpha-helical peptides that kill cells by disrupting the cell membrane. Recently, we have been studying a simple 'designed'... -
Solution aggregation of lipopeptides: SANS structure determination
Lipopeptide surfactants are highly effective at reducing interfacial tension. However, there is a general lack of understanding of the relationship between their molecular... -
Benchmarking improvements in experimental design in neutron reflectometry
This dataset has no description
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Investigation of zwitterionic surfactant, Ca2+ and bio-polymer interactions
We are currently investigating the formation and structure of surfactant-templated polymer films comprised of cat-anionic surfactant mixtures and a variety of polymers. As we... -
A complex model of the bacterial outer membrane containing oriented proteins ...
The Outer Membrane (OM) is found in bacteria which cause plague, cholera & Legionnaire?s disease. It is important as; a barrier to antibiotics & the site of... -
A model of the bacterial outer membrane containing both Outer Membrane Protei...
We have recently improved the stability and coverage of free standing bilayers (FSB) by the use of a supporting thiolipid layer on gold. The system has been investigated on... -
Self-assembled Floating Lipid Bilayers: What Forces Are Causing the Bilayer t...
Recently (RB19100102) we have discovered that floating bilayers composed of fluid phase lipids can be produced by deposited vesicles onto charge modified oligo(ethylene... -
Sustainable polymeric deposition aids
This is a new programme of work and a collaboration between CCLRC, Oxford, Unilever and Manchester. It is concerned with polymer aided deposition to solid substrates, using... -
Formation of asymmetric free-standing bilayers with lipopolysaccharide in the...
We have recently improved the stability and coverage of free standing bilayers by the use of a supporting thiolipid layer on gold. The system has been investigated on POLREF and...