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Supplementary Video 1
Video showing how 24 hpf body explants have beating hearts and undergo normal heart development until 48 hpf:Wholemount timelapse movies of beating hearts and blood flow in 24... -
Supplementary Video 3
Thin cECM regions run extensively across the myocardium in a 48 hpf ventricle:Video showing the rotating maximum intensity projection of a 48 hpf heart created with Imaris. -
Supplementary Video 4
Thin cECM regions are stable across heart beats: Video showing the maximum intensity projection of a 48 hpf beating heart temporally registered with Beatsync, acquired at 100... -
Supplementary Video 5
Cells delaminate into thin cECM regions at 55 hpf: Video showing the rotating maximum intensity projection of a 55 hpf heart created with Imaris. Delaminating cells... -
Supplementary Video 6
24 hpf beating heart showing the optical resolution with the body explant method Video showing a maximum intensity projection of a beating 24 hpf heart temporally registered... -
Supplementary Video 7
cECM is homogenous at 24 hpf and starts to remodel at 30 hpf Midsagittal timelapse movies of a 24 hpf and 30 hpf heart, acquired at 100 fps. Asterisks indicate areas of thin cECM. -
Supplementary Video 9
Strain maps of a beating 48 hpf heart showing higher strain in the outer curvature -
Supplementary Video 10
Simulated cECM fracture dynamics of a beating 48 hpf heart showing fractures emerging in the outer curvature -
Supplementary Video 11
Strain maps of a beating 48 hpf amhc morphant heart showing lower strain -
Supplementary Video 12
Simulated cECM fracture dynamics of a beating 48 hpf amhc morphant heart showing less fractures emerging -
Supplementary Video 13
Strain maps of beating 30, 36 and 42 hpf hearts showing the shift in strain patterns as ventricle geometry evolves -
Supplementary Video 15
Strain maps of a beating 48 hpf tbx5a morphant heart showing homogenous strain aligned perpendicular to the long axis of the heart -
Supplementary Video 16
Simulated cECM fracture dynamics of a beating 48 hpf tbx5a morphant heart showing linear fractures running along the long axis of the heart -
Supplementary Video 14
Simulated cECM fracture dynamics of beating 30, 36 and 42 hpf hearts showing the shift in cECM fracture patterns as ventricle geometry evolves -
Supplementary Video 8
Nuclei tracks of a beating 48 hpf heart Video showing tracked nuclei in a maximum intensity projection of a beating 48 hpf heart, temporally registered with Beatsync. Nuclei... -
Supplementary Video 2
Video showing surgical removal of the zebrafish head at 30 hpf. Zebrafish labelled with fli:GFP, showing vasculature and beating heart endocardium. Due to the depth of cardiac...
