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The mechanism of lipid transport in Gram-negative bacteria
The bacterial cell envelope is one of the best targets for antimicrobial development. It is this envelope that harbours the instruments of microbial warfare, preventing its... -
Monolayer behaviour of DMPC and DEHP with cholesterol
Donated blood is typically stored in bags made of PVC plasticized with DEHP. DEHP migrates into the blood and the amount in the blood cells can be 5 to 10% of the phospholipid... -
Neutron Reflectivity Study of NeutrAvidin Immobilised onto Ti Implant Surfaces
We ask for 3 days of beam time on Inter/SURF to study the adsorption and adlayer characteristics of avidin on Ti surfaces, relevant for biomedical applications, such as... -
Temperature-induced structural changes of Organic Friction Modifier films at ...
Engine oils provide lubrication to moving components in engines, improving vehicle lifespans whilst reducing emissions and fuel consumption by minimising friction. A common... -
Interfacial conformation of antibody and antigen binding capacity
Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element... -
Structure of yeast lipid monolayers and the effects of Amphotericin B
We have recently developed methods for the extraction, separation and analysis of lipids from yeast cell cultures as physiologically realistic targets for membrane binding drugs... -
Effect of structure on the location of hydrophobic drugs in ionic surfactant ...
Many drugs are both poorly water-soluble (hydrophobic) and lipophilic in nature and are therefore incorporated into surfactant micelles and monolayers. As the incorporation of... -
Floating Bilayer Mimics of the Gram Negative Bacterial Outer Membrane
The gram-negative bacterial membrane is of extreme medical importance. The two main lipid components of the outer membrane are lipopolysaccharides (LPS's) and DOPE. We will... -
Tailored interfacial properties of battery electrodes
Consisting of a positive and negative electrode, conventional batteries undergo a range of static and dynamic processes that originate at the electrode surface. As such,... -
Structural characterisation of an electron-transfer protein, cytochrome c, on...
This proposal concerns the adsorption behaviour of an electron-transfer protein, cytochrome c, on modified electrode surfaces. Cytochrome c plays an important role in... -
What is the reactivity of marine atmospheric aerosol to oxidation? A study of...
The Earth's climate is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects droplet size and optical properties, important effects. Common... -
Interfacial structures and competitive adsorption of amphiphilic polymers wit...
Foam stability, appearance and functionality is governed by the thin liquid films between foam bubbles. These films are stabilised by surface active molecules (surfactants and... -
Surface Smectic Layers in difluoroterphenyls
The proposal is to use previous established neutron reflection methods to observe the smectic layers that form at the surface of a nematic liquid crystal. In this proposal we... -
INTERACTIONS OF PAMAM DENDRIMERS WITH DESIGNER BIOSURFACTANTS AT THE SOLID/LI...
Poly(amidoamine) (PAMAM) dendrimers have been identified as potential gene vectors. We have studied their association with surfactants, dilauroylphospholiponucleosides (DLPN),... -
Does spinodal dewetting proceed by peristalsis?
We shall demonstrate the use of neutron reflectometry to obtain three-dimensional structures in a non-invasive experiment. Spinodal dewetting is one of the few areas where... -
Impact of surfactant interactions on fate of marine aerosols: NO3-initiated o...
Mixed films of palmitic acid (PA) and galactocerebrosides (GCB) a proxy for marine aerosol exhibit attractive interactions due to H-bonding of galactose and carbonyl head... -
Morphological Stability of Organic Solar Cell Structures during Aging
Organic photovoltaics (OPVs) have recently surpassed 10% power conversion efficiency (PCE), a key milestone towards commercialisation. Achieving validated lifetimes beyond 10... -
Scaling Model for the adsorption of macromolecules at the oil-water interface
The aim of this proposal is the application of the scaling model for the adsorption of proteins at the oil-water interface. The adsorbed amount for a series of oils as a... -
Interfacial adsorption of keratin as characterised by neutron reflection
This proposal constitutes part of our ongoing study towards understanding the adsorption of keratins and their interactions with ionic surfactants at the solid/water interface.... -
Copy of: The origins of Biosurfactant self synergy
Biosurfactants are becoming more commonplace in pharmaceuticals, vaccines and other forms of medicines. With the biobased economy growing substantially and pressure to reduce...
