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Competetive adsorption in hydrophobin / protein mixtures at the air-solution ...
Hydrophobins are secreted fungal proteins in the form of small lipopetide biosurfactants. They are strongly surface active and self assemble at interfaces and in solution. This... -
The Kinetics of Self-Exchange of a Protein at Solid/Liquid interfaces
The formation of a protein corona occurs on all surfaces exposed to biological systems and understanding of how this corona forms is vital for many aspects of medicine and for... -
Dirac Point and Topological Triplon Bands in the Shastry-Sutherland Material ...
SrCu$_2$(BO$_3$)$_2$ (SCBO) is a very much studied quantum magnet that is most well known for its ground state of coupled singlets and multiple magnetization plateaux. Recently,... -
Organisation of Outer membrane protein F at the air/liquid interface
Crystallisation of membrane proteins as a precursor to high resolution structural studies is a significant research bottleneck. We are investigating alternative methods to... -
Dynamics of amyloid protein fibril growth using isotope-labelled SANS
This proposal aims use a novel approach whereby deuterated amyloid peptide fibrils are givenhydrogenated growing ends, and analysed using SANS. The data will enable us to... -
Structural Study of Functional Nucleosome in Solution
Recently, it is reported that the functional nucleosomes, CENP-A nucleosome, H2A.Bbd nucleosome and hexasome, which include variant histone cores, could have flexible and mobile... -
Solution structures of three immunologically important proteins IgA, C3 and IgG
Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its... -
How do colloidal nanocrystals appear to biological systems? A SANS study of t...
A key aspect of any biological application of nanomaterials is to understand what happens when they are introduced into biological environments. When particles are introduced... -
Further SANS contrast measurements on important protein/DNA interactions from...
This proposal is to perform further SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an... -
OB Buffer - 40% D2O_SANS
This dataset has no description
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Dynamics of trehalose-glycerol and lysozyme/trehalose-glycerol mixtures
The proposed experiment aims to study the dynamics of trehalose/glycerol mixtures and lysozyme in presence of trehalose/glycerol mixtures at different relative concentration.... -
Solution Structure of the OmpF-TolA complex
Gram negative bacteria cause a wide range of diseases including meningitis, bubonic plague, gonorrhoea, diarrhoea, Legionnaires' disease and cholera. Their outer membrane... -
Understanding the true biological function of Plant Non Specific Lipid Transf...
Non specific lipid transfer proteins are a family of basic, cysteine rich proteins found in a wide range of plant species. The biotechnological role of these proteins in beer... -
Conformational change of glycerol faciliitator protein on substrate binding
A large family of membrane channel proteins selective for transport of water (aquaporins) or water plus glycerol (aquaglyceroporins) has been found in diverse life forms. E.... -
Supramolecular assemblies of arginine and their impact on protein aggregation
Arginine is an important molecule which utilised in industrial, biochemical and medical research to aid in the successful refolding of proteins and to resist the effects of... -
Characterisation of bioadhesive protein-PEG conjugates grafted to titanium su...
Summary: Titanium implants are surgically important and require a hydrophilic polymer coating to prevent biofouling in situ. Bioadhesive proteins can be covalently tethered to... -
Neutron scattering study on dynamics of cytochrome c in MCM41
Studies of internal dynamics in the pico seconds timescale, of cyt c trapped in MCM-41, would allow the forms, geometry, amplitudes and time-dependence of the motions involved... -
Further SANS contrast measurements on important protein/DNA interactions from...
This proposal is to perform further SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an... -
A study of protein adsorption via chelating lipids within a solid supported l...
The crystallisation of membrane proteins is of great interest, not least, to the pharmaceutical industry. We have recently begun a project aiming to investigate the role played... -
Oriented antibody binding layers
The proposal concerns the assembly of high density antibody binding surfaces to increase the sensitivity of medical diagnostics. Previously we showed that antibody binding...
