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Planar bilayer formation on novel cationic surface suitable for membrane prot...
Membrane receptor proteins (MRPs) which are thought to represent the majority of drug targets are challenging to study as their structure and function is dependent on being... -
The Kinetics of Self-Exchange of a Protein at Solid/Liquid interfaces
The formation of a protein corona occurs on all surfaces exposed to biological systems and understanding of how this corona forms is vital for many aspects of medicine and for... -
How polymer functionality influences multilayer formation at the interface in...
Spontaneous multilayer formation at interfaces from surfactant self assembly is emerging as an important structural signature associated with a wide range of potential... -
The hydrophobic interaction A peptides and a lipid monolayer at the o...
This proposal relates to the study on the fundamental level, the hydrophobic interaction A peptides and a lipid monolayer at the oil-water interface. NR will be used to... -
Molecular architecture of monolayers formed by novel sterol-modified phosphol...
A family of sterol-modified glycerophospholipids (SML) have been synthesized in which the sn-1 or sn-2 position is covalently attached to cholesterol and the alternative... -
Phase behaviour in Polymer-Photovoltaic Thin Film Blends
In polymer-fullerene based photovoltaic systems the phase behaviour of the blends is poorly understood and remains a fundamental stumbling block to improvements in device... -
Electric field induced swelling/collapse of strong polyelectrolyte brushes
Electric field induced changes in the swelling of a strong polyelectrolyte brush will be investigated using neutron reflectivity. A poly(styrene sulphonate), PSS, brush will be... -
Study of the interaction of thermoresponsive naogels with lipids
This proposal seeks to characterise the hydrophobic interaction of thermoresponsive nanogels designed for drug delivery through the skin with a lipid monolayer as a function of... -
Bilayer modification and charge screening by simple ions
Calcium ions have been shown in a preliminary experiment to have a dramatic effect on the thickness and structure of free supported DPPC bilayer films. At low concentrations... -
Effect of Aging Temperature on Inorganic Films Templated by Polymer-Surfactan...
Recently we have been investigating the mineralization of polymer-surfactant films to create thicker and more robust self-supporting membranes. Our previous experiments used the... -
Incorporation of PAN-pyrene swollen micelles in crosslinked polyelectrolyte f...
We have been studying the formation of solid polymer-surfactant films at the air-solution interface formed from cationic surfactants with PEI. We wish to use the micelles... -
The interaction of oxidatively damaged lung proteins with anionic lipids
Lung surfactant protein B, SP-B, interacts with lipids at the air-water interface of the lung where its presence is vital for correct respiratory function. SP-B and its... -
Understanding the true biological function of Plant Non Specific Lipid Transf...
Non specific lipid transfer proteins are a family of basic, cysteine rich proteins found in a wide range of plant species. The biotechnological role of these proteins in beer... -
Surfactant and Polymer Adsorption on Pyrite Thin Films
Pyrite (FeS2) is a hydrophobic mineral surface, i.e. of a type thus far inaccessible to the types of aqueous adsorption experiments suitable for study by reflectometry (NR), but... -
Understanding the nature of perfume / surfactant interactions at interfaces
This proposal is part of a funded (CASE) project, aimed at understanding the delivery of benefit actives (perfumes) to interfaces and the development of new self-assembled... -
Conformational change of glycerol faciliitator protein on substrate binding
A large family of membrane channel proteins selective for transport of water (aquaporins) or water plus glycerol (aquaglyceroporins) has been found in diverse life forms. E.... -
Measurement of the Casimir Force
There is a great deal of interest in the Casimir force due its connection with quantum fluctuations, dark energy and nanotechnology applications. Measurements in plate geometry... -
The effect of fatty acids on the adsorption of HSA at the silica water interface
The primary biological function of albumins is to be fatty acid carriers. The complexation of fatty acids to the albumin is expected to have a strong effect on its adsorption... -
Gas-phase oxidation of insoluble monolayer at air-water interface with no equ...
The Earth¿s climate is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects cloud droplet size and optical properties, important climatic... -
quenching and partitioning the new heat-treatment porcess
quenching and partitioning the new heat-treatment porcess
