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Kinetics of surfactant multilayer formation / dissolution at interfaces
The formation of multilayer structures at surfaces and interfaces from self-assembly in mixed surfactant and in polymer / surfactant mixtures has been recently reported, and... -
Competetive adsorption in hydrophobin / protein mixtures at the air-solution ...
Hydrophobins are secreted fungal proteins in the form of small lipopetide biosurfactants. They are strongly surface active and self assemble at interfaces and in solution. This... -
SANS Study of pH-Triggered Behaviour in Pluronic-Flurbiprofen Solutions: In v...
Hydrophobic drug encapsulation is one of the widely used strategies to overcome the poor adsorption and bioavailability of these drugs in vivo. Water-soluble amphiphilic... -
Molecular Mechanistic Processes of Complexation between DNA and Cationic Copo...
We have previously used LOQ to identify the complex (polyplex) structures formed between a short single strand DNA and a cationic diblock copolymer MPC30-DEA60. The SANS... -
Effects of pH and ionic strength on stability and structure of lipid-polymer ...
Nanostructured lipid aggregates offer enormous potential as tools for membrane structural biology and biophysics. Styrene-Maleic Acid Lipid Particles have a number of attractive... -
Interfacial adsorption of keratin as characterised by neutron reflection
This proposal constitutes part of our ongoing study towards understanding the adsorption of keratins and their interactions with ionic surfactants at the solid/water interface.... -
Membrane interactions of a viral scission protein
Influenza virus is a pathogen of great medical importance that causes seasonal epidemics and sporadic pandemics. Among the least understood events of the influenza virus... -
pH-driven self-assembly of colloidal particles confined between parallel walls
Small particles with dimensions of a few hundred nanometers tend to behave differently when confined in small spaces. Examples of such situations are easy to find in nature --... -
Interfacial layer structure of designed linear lipopeptides
Lipopeptide surfactants are a group of interesting biosurfactants due to their natural origin and their high effectiveness at reducing interfacial tension. However, there is a... -
Probing the interactions of chitosan with lipid bilayers to elucidate its ant...
Chitosan is a linear polysaccharide that is biocompatible and biodegradable. Chitosan has a number of unique chemical and biological features including its cationic nature and... -
Adsorption and activity of Thermomyces lanuginosus Lipase (TLL) at the oilwat...
The purpose with the proposed project is to provide a better understanding of structural changes in interfacial lipid layers due action of lipolytic enzymes. In this study we... -
Cationic surfactants adsorbed to titanium dioxide-effect of pH and added elec...
Titanium dioxide (TiO2) is used in a wide range of applications from medical and dental implants to treatment of contaminated air and water streams. However many of the... -
Structural Studies on Aggregates Formed by Novel Star-Shaped Oligomeric Surfa...
Oligomeric surfactants, where three or more alkyl chains and headgroups are connected via spacer groups with various geometries, have interesting and potentially important... -
Solution aggregation of short peptide amphiphiles
Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly to lead to interfacial adsorption and solution nano-aggregation.... -
Interfacial conformation of antibody and antigen binding capacity
Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element... -
A Reversible pH-Driven DNA Nanoswitch
DNA is an extremely versatile building material for the development and assembly of functional nanostructures and nanodevices. There are numerous examples of DNA based... -
Impact of Protein Nanosheet Structure on Nanoscale Toughness
Cell adhesion and proliferation at the surface of liquids such as oil droplets is a surprising phenomenon as it is typically accepted in the field of bioengineering that cells... -
Effect of calcium ions and ionic strength on model bilayer structure
Calcium ions have been shown in a preliminary experiment to have a dramatic effect on the thickness and structure of free supported bilayer films. In this proposal we... -
Study of Small molecule effects on AB interactions with model lipid layer by ...
Neutron reflectometery will be used to provide the vital information about the interaction/conformation of the organophosphonate compound on the lipid structure in the... -
Micelle structures in unequal mixtures of amino-acid surfactants
In a previous proposal we started to study the micellar structures formed from biodegradable surfactants synthesised using amino acids as the headgroups. The aim of this work is...