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Solution Structure of the OmpF-TolA complex
Gram negative bacteria cause a wide range of diseases including meningitis, bubonic plague, gonorrhoea, diarrhoea, Legionnaires' disease and cholera. Their outer membrane... -
The interaction of oxidatively damaged lung proteins with anionic lipids
Lung surfactant protein B, SP-B, interacts with lipids at the air-water interface of the lung where its presence is vital for correct respiratory function. SP-B and its... -
Understanding the true biological function of Plant Non Specific Lipid Transf...
Non specific lipid transfer proteins are a family of basic, cysteine rich proteins found in a wide range of plant species. The biotechnological role of these proteins in beer... -
Structure of chain-grafted silica nanoparticles
The aim of the proposed experiment is to carry out a series of SANS measurements on chain-grafted silica nanoparticles prepared in our laboratory. In this experiment we plan to... -
Study of pore-confined CO2 depletion below the bulk triple point
Freezing of fluids confined at the nanoscale is of great importance for the understanding of their behaviour due to the confinement effects arising from the finite pore size and... -
Investigation on the self-assembling of amphiphilic peptides
This dataset has no description
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Oil disperse phospholipid stabilised microemulsions prepared using non-aqueou...
It is the aim of the proposal is to perform small angle neutron scattering (SANS) studies combined with contrast variation to determine the size and structure of the... -
Unravelling the thermal denaturation and stability of the solution structures...
The glycosylation of glycoproteins is a major determinant of their stability, and glycans also affect their aggregatibility (precipitation). An understanding of this is... -
Understanding the microstructure of polymer blends used as control release co...
Solid oral dosage forms consist of polymer layer encapsulated drug-bound particles with a desired drug release profile e.g. pulsatile, controlled, delayed and targeted,... -
Lipid bilayers suspended beneath the air/water interface for neutron reflecti...
Bacterial membranes contain safety valves called mechanosensitive ion channels, which protect the bacterium from changes in the osmotic pressure of their environment. However,... -
Adsorption of Bispecific Monoclonal Antibodies with Extended Domains at the O...
Following our previous study of interfacial adsorption of the basic version mAb COE-3, we wish to continue this work by exploring how two modified mAbs adsorb at the same... -
Interaction of amino acid based biosurfactants with model lipid bilayers
N-acyl amino acids are surfactants with attractive applications in different technological fields. They are referred to as mild surfactants because they are commonly considered... -
Kinetic Study of the Mechanistic Complexation Process Between DNA and Cationi...
We propose to use the new SANS2d to study the dynamic structural evolution in the couse of the formation of DNA-cationic polymer complexes. The dynamic process and the mixing... -
Free Floating Higher Plant Membrane Mimetics
We have engaged in a long term effort to build accurate bio-mimetic systems for complex structural biology studies. Recently, we have found that thiolalkylamidealcohol... -
In situ study of destruction of a denatured surface protein by protease (Savi...
New detergents will increasingly rely on sustainable products and the use of enzymes will become ever more important. However, the process of destruction of stains (often... -
Protein secretion: Studying the folding and assembly of membrane proteins usi...
This dataset has no description
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Probing the interactions of chitosan with lipid bilayers to elucidate its ant...
Chitosan is a linear polysaccharide that is biocompatible and biodegradable. Chitosan has a number of unique chemical and biological features including its cationic nature and... -
Adsorption of bioengineered antibodies at the oil/water interface
Following our previous study of interfacial adsorption of the basic version mAb COE-3, we wish to continue this work by exploring how two modified mAbs adsorb at the same... -
Characterising the amorphicity and porosity of ice aggregates in planet-formi...
With the discovery of almost 3000 exo-planets it is clear that planet formation is a by-product of star formation, yet in the micron ? cm size range, where relative velocities... -
Solid-supported lipid bilayers for studying mechanosensitive ion channels: to...
Bacterial membranes contain safety valves called mechanosensitive ion channels, which protect the bacterium from changes in the osmotic pressure of their environment. However,...
