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Effect of saponin-rich plant extracts on skin-mimicking model lipid bilayers
Plant-derived biosurfactants of the group of saponins offer an attractive alternative to synthetic surfactants because of their unique foaming and emulsifying properties... -
Understanding the molecular origin of co-non-solvency. Step 2.
A number of polymers that are commonly soluble in water and in alcohol, display a dramatic collapse when 10 molar % of alcohol is added to the polymer/water system. Various... -
Optimisation of a novel biosensor: the structure of the sensing layer
This dataset has no description
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Satisfying the need for contrast in antimicrobial research
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
DRUG EFFECTS ON INTRACELLULAR WATER DYNAMICS: CISPLATIN IN HUMAN CANCER CELLS
Water dynamics plays a vital role in biochemical processes in a living organism. Intracellular water structure and dynamics are known to be changed by the presence of... -
Membrane-stacking properties of myelin proteins
Myelin is the multilamellar structure that ensheaths axons and accelerates nervous impulses in the nervous system. The fine structure of myelin remains to be further... -
Competitive adsorption of a Biosurfactant conventional surfactant mixture at ...
We propose to study the competitive adsorption of a biosurfactant conventional surfactant mixture at the surface of an emulsion droplet in order to determine how these two... -
Surfactant Modified Salivary Pellicles
Salivary films are (mostly) proteinaceous nm-thick films that form on any type of surface upon exposure to saliva. The role of the pellicle is manifold. Among its functions,... -
Feasibility studies of neutron protein crystallography at ISIS using perdeute...
We propose to use instruments SXD and WISH to carry out a detailed feasibility study of neutron protein crystallography at ISIS. Since one of the major impediments to protein... -
Solid-supported lipid bilayers for studying mechanosensitive ion channels: to...
Bacterial membranes contain safety valves called mechanosensitive ion channels, which protect the bacterium from changes in the osmotic pressure of their environment. However,... -
How do Polymer Stabilized Nanodiscs Form?
Nanodiscs are self-assembled structures composed of phospholipids stabilised by a polymer belt. They are capable of encapsulating single membrane proteins and as such have many... -
Investigating the structure of bulk metallic glasses using isotopic substitution
We propose to undertake calcium isotopic substitution on two Mg-Zn-Ca bulk metallic glasses which show considerable promise for use as medical implants. Glasses in the Mg-Zn-Ca... -
Membrane interactions of a viral scission protein
Influenza virus is a pathogen of great medical importance that causes seasonal epidemics and sporadic pandemics. Among the least understood events of the influenza virus... -
Effect of drug structure on solubilisation in a range of surfactant micelles
The aim of the current project is to probe (at the nanometer length scale) the relationship between the structure of a surfactant molecule, the micelles it forms in solution,... -
Unravelling the ageing mechanims of dry seeds: molecular mobility within biol...
Faster-than-expected ageing is observed in some seeds (e.g. orchids, coffee, citrus, willows) stored dry at -20°C, the standard temperatures of seed banks. This ageing has been... -
Investigation on the air-water adsorption behaviour of N-acyl amino acid surf...
N-acyl amino acids are promising anionic amphiphilic molecules with an improved toxicological profile in comparison to the most common used sulfate-based surfactants. Previous... -
The location of an essential ceramide for skin barrier function within the lo...
The body is protected from the external environment by the stratum corneum (SC) layer of the skin. It is believed that the lamellar lipid matrix, which encases the corneocytes,... -
Effects of Antimicrobial Peptide on the Dynamics of Anionic Phospholipid Memb...
This dataset has no description
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A comparative NR study of interaction of short designed antimicrobial peptide...
The global increase of bacterial resistance to antibiotics has led to increasing interest in research focusing on the development and characterization of new antimicrobial... -
Antimicrobial peptide folding and unfolding in solution
This dataset has no description
