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Understanding the insertion of antibiotic toxins into the gram negative outer...
The gram-negative bacterial membrane is of extreme medical importance. Two of its major components are lipopolysaccharides (LPS's) and integral membrane proteins. Porins are... -
The effect of dendrimer surface functionalization on the interaction with mod...
Dendrimers are a unique class of nano-structured vehicles for drug and gene delivery into intracellular targets. Their surface chemistry influences their transport across... -
Laser-induced electron transfer in Trp-Tyr
We wish to perform longitudinal field measurements on the dipeptide Trp-Tyr under laserexcitation, to probe the electron transfer process within the molecule. We have already... -
Investigation of excitonic physics in polycyclic aromatic hydrocarbon molecules
The MuSES project currently ongoing in the HiFi spectrometer gives unique opportunity in the field of photochemistry and photophysics of organic molecules. After two successful... -
Nanodiscs films at the air-water interface
Nanodiscs are self assembled complexes of phospholipids and a class of amphipathic helical proteins termed membrane scaffold proteins . The proteins and lipids self-assemble... -
Excited/Ground State of Kekulé di-radical Material Bisphenalenyl
Kekulé di-radical (KDR) with two radical centers of independent spins has a low-spin ground state (singlet S0 with antiparallel spins), and interestingly high-spin triplets (T1)... -
The Mechanism and Kinetics of Lipid Flip-Flop in Floating Phosphatidylcholine...
In order to maintain their asymmetric lipid distribution, cellular membranes have a number of means to translocate lipid molecules across the bilayer. On top of the well-studied... -
Effects of Architecture on Polymer Diffusion
As part of a wider study we are studying the effects of polymer architecture between cyclic and linear polymers. From ATR-FTIR measurements we observe clear differences between... -
Neutron Reflectivity Study on Multi-domain DNA Molecular Motors
DNA is a versatile building material for nanotechnology. We have recently studied a surface-tethered single-domain DNA motor by neutron reflection (IR) for the first time. We... -
A Reversible pH-Driven DNA Nanoswitch
DNA is an extremely versatile building material for the development and assembly of functional nanostructures and nanodevices. There are numerous examples of DNA based... -
Application of Superpace methods to long period Perovskite superstructures
Recently there have been considerable several reports of ¿nanostructured¿ perovskite oxides. In order to obtain detailed knowledge of the factors controlling the formation of... -
Kinetics and growth mode of aggregation phenomena inside polymer brushes
We will use time-resolved specular neutron reflectivity measurements to follow the in-situ growth of polymer brushes by surface-initiated ATRP. This will enable us to determine... -
Investigating the ALCs of organic-inorganic hybrid semiconductors under elect...
The push globally for greener energy supplies has led to the discovery of new solar cell materials, which consist of an organic molecule surrounded by eight PbX5 octahedras... -
Structure and activity of Membrane Proteins immobilised to solid supports.
Membrane Proteins (MPs) consist of about 1/3 of the proteome but the structural information available is very limited compared to that for soluble proteins. Despite this at... -
Effects of Architecture on Polymer Diffusion
As part of a wider study we are investigating the effects of polymer architecture between cyclic and linear polymers. From ATR-FTIR measurements we observe clear differences... -
Muonium-photocarrier interaction in germanium
Having established the photo-MuSR method in intrinsic silicon to investigate excess carrier recombination lifetime and Mu-photocarrier dynamics in our previous experiments, we... -
Detection of Spin-Polarized Conduction Electrons in Si by MuSR
One of the challenges of developing Silicon-based spintronics technology is developing non-destructive methods for characterizing spin-polarized conduction electrons. Si is... -
The hydration and ordering of lamellar block copolymer films prior to the for...
For polymer vesicles to act as effective molecular delivery systems we must efficiently encapsulate a molecular payload within the vesicle. We would like to use neutron... -
Searching for a core-shell or multi shell structure in Stöber silica particles
We want to measure the SESANS from a series of large ~1 micron silica particles formed using the multistage Stöber method. The reason for this is to determine if we can see the... -
Reflectometry studies of the mechanism of formation of mesoporous silicate fi...
Surfactant-silica self-assembly processes have been extensively studied since the discovery of M41S mesoporous materials in 1992. Mesoporous silicate films can be grown from...