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Dynamics of Protein-Confined Water in Polymer Vesicles: A Feasibility Study
When we confine water in extremely small spaces it starts to move extremely slowly. This behaviour is critical to helping biological molecules like proteins function normally.... -
Kinetics of protein and protein mixture adsorption at the air/water interface
Many proteins exhibit a lag in lowering the surface tension at the air-water interface. The origin of this lag is not well understood either experimentally or theoretically. The... -
The solution structure of the OmpF¿Colicin N complex in neutral detergent by ...
Gram negative bacteria cause a wide range of diseases. Colicins are protein toxins capable of penetrating the outer membrane barrier and killing the bacteria. Thus they... -
Modelling the Intracellular Lipid Shuttling Mechanism of Non Specific Lipid T...
Previously we have examined the interaction of barley non-specific lipid transfer protein (nsLTP1) with OTS and lipid monolayers at the solid/liquid interface. Examining the... -
Solution structures of the immunologically important proteins IgA, C3 and IgG
Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its... -
INS investigation of the effects of hydration on the dynamics of natural silk...
Silk materials have been the focus of renewed attention because they exhibit extraordinary mechanical strength and toughness.Two main factors are critical for understanding... -
Modes of protein adsorption at polyethylene oxide brushes of various polymer ...
We wish to understand the mechanism to which polymer brushes such as PEO resist the adsorption of protein and thus offer biocompatibility for various surface applications.... -
b-crystallin 25C 002
This dataset has no description
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SANS contrast measurements on important protein/DNA interactions from RCaH
This proposal is to perform SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an ongoing... -
Structural development in Whey protein polymer composite solutions for electr...
This is part of an on-going investigation into nano/micro scale sized polymer fibres at the University of Reading, prepared through the process of electrospinning. Currently we... -
Structural studies of protein at the oil-water interface
We would like to measure the adsorption isotherm for protein, milk B-casein using neutron reflectometery at the oil-water interface. These measurements will be carried out for... -
The solution structure of the OmpF¿Colicin N complex in neutral detergent by ...
Gram negative bacteria cause a wide range of diseases including meningitis, bubonic plague, gonorrhoea, diarrhoea, Legionnaires' disease and cholera. Their outer membrane... -
Transition and signature of protein domain motion in Phosphoglyceratekinase (...
In a series of neutron spin-echo experiments (NSE) on the proteins alcohol dehydrogenase (ADH) and phosphoglycerate kinase (PGK) large scale large amplitude domain motions with... -
Structural characterization of a series of polymer-protein conjugates for chr...
Polymer-protein conjugates have been designed to deliver an appropriate target growth factor to promote a more rapid healing of chronic wounds, an incredibly important area for... -
Probing the Kinetics of Assembly and Triggered Dispersion of Peptide-Function...
Peptide-functionalized nanoparticle (NP) aggregates have significant potential as biosensors (for specific enzymes) due to their high sensitivity, modular design and simple... -
Conformational changes on interaction of cytochrome c with lipid monolayers.
The main objective of the present work is to gain an understanding of the interaction of the cationic protein, cyt c with anionic lipid membranes. This objective will be... -
Study of the protein denaturation in glassy matrices
The proposed experiment is addressed to use the MARI spectrometer to study the thermal denaturation process of the psychrophile enzyme alpha-amylase in presence of bioprotectant... -
Solution structures of the immunologically important proteins IgG and C3b
IgG antibody represents one-third of new drugs currently in development. We will unravel the solution structures of the Fab and Fc fragments within IgG. Following our earlier... -
Using neutron crystallography for investigating protonation states of a catal...
Chlorite dismutases (Clds) are metalloproteins containing heme b (i.e. Fe(III) in a porphyrin system) as redox cofactor. Clds are able to degrade toxic chlorite to chloride and... -
Kinetics of casein aggregation in H2O and D2O
Dairy products are formed by coagulating milk particles and their texture is determined by the mechanism and kinetics in which structure is formed. Yogurt is formed by gelation...
