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Neutron reflectometry of an atopic dermatitis stratum corneum skin model
Atopic dermatitis (AD) is a chronic inflammatory skin condition affecting up to 20% of children and 3% of adults, resulting in significant reduction in quality of life and costs... -
Polarised Neutron Reflectometry from Frustrated Nanomagnet Arrays
We propose to study off-specular polarised neutron reflectivity from an array of CoFeB nanostructures. Many groups use Permalloy to form these types of nanostructures, however,... -
Kinetics of protein and protein mixture adsorption at the air/water interface
Many proteins exhibit a lag in lowering the surface tension at the air-water interface. The origin of this lag is not well understood either experimentally or theoretically. The... -
Adsorption of Fab and Fc from monoclonal antibody at the oil/water interface
Following our previous study of adsorption of globular lysozyme and BSA, we continue to explore how different globular proteins adsorb at the oil/water interface by neutron... -
Scaling Model for the adsorption of macromolecules at the oil-water interface
The aim of this proposal is the application of the scaling model for the adsorption of proteins at the oil-water interface. The adsorbed amount for a series of oils as a... -
Binding behaviour of PAMAMs G5 and G4.5 to zwitterionic and anionic lipid bil...
Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug... -
Proteins of Different Size and Globular Stability Adsorbed at Oil/Water Inter...
In this work we explore how to use neutron reflection to study protein adsorption at the oil/water interface. Inter is preferred because we have built technical capability on... -
Antibiotic Interactions with models of the Gram negative bacterial outer memb...
Gram-negative bacteria, which cause a variety of diseases including meningitis, plague, sepsis and food poisoning, are becoming increasingly antibiotic resistant. One reason is... -
Lipid monolayers at oil/water interfaces at high surface pressure as model bi...
This dataset has no description
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Insertion of antimicrobial peptides into phospholipid monolayers at air/liqui...
We have designed a series of cationic peptides with different helix repeats that can kill bacteria but remain benign to mammalian host cells. The selectivity to cell types is... -
pH-control of swelling and charge neutralization of thin hydrogel films
Hydrogels are widely used in biomaterials science, much due to excellent protein resistance, and physicochemical properties similar to biological tissue. Charge neutrality is... -
Self-Organisation of Phospholipids on Au Electrodes
This experiment is part of a programme to study the effect of applied electric fields on the structure of biomimetic films formed at Au electrodes, with emphasis on... -
Smectic Wetting at Nematic Surfaces
We have been studying the interaction between nematic liquid crystals and interfaces. It has been found that a surface that anchors the director in a perpendicular orientation... -
Interaction between RNA and lipid monolayers
The objective of the suggested study is to reveal the structure formed when short ssRNA molecules (similar to miRNA) interact with lipid monolayers at the air-water interface.... -
Recreating the specific colicin NRa-LPS interaction in a model bacterial out...
The Gram negative bacterial outer membrane protects the bacterium from external toxins such as antibiotics. This is partially responsible for Gram negative bacteria becoming the... -
Structural studies of protein at the oil-water interface
We would like to measure the adsorption isotherm for protein, milk B-casein using neutron reflectometery at the oil-water interface. These measurements will be carried out for... -
Do hydroxyl radicals penetrate the organic monolayer at the air-water interface?
The Earth¿s climate is strongly influenced by clouds. The oxidative processing of pollutants in clouds affects droplet size and optical properties, important climatic effects.... -
Structure of a cationic polyelectrolyte adsorbed at an oppositely charged sur...
Adsorption of a charged polyelectrolyte onto an oppositely charged substrate is important for the understanding of many natural molecular events as well as for the development... -
Magnetism in novel organic/inorganic hybrid spin-valve nanostructures.
We request 5 days (15 shifts) with CRISP to perform specular measurements on novel functionalized SrTiO3(substrate)/complex FM oxide/small molecules/ FM metal nanostructures to... -
Lipid monolayers at oil/water interfaces at high surface pressure as model bi...
This dataset has no description
