29 datasets found

Bacterial lipopolysaccharide (LPS) is a bioactive structural amphiphilic molecule which forms the outer leaflet of the outer membrane of the Gram negative cell envelope. During...

Dendrimersomes are an exciting new class of vesicles, comprising bilayers of dendrimer molecules that can be engineered to have sensitivity to e.g. changes in pH and enzymes....

We have previously used LOQ to identify the complex (polyplex) structures formed between a short single strand DNA and a cationic diblock copolymer MPC30-DEA60. The SANS...

Cytochromes P450 play a key role in drug metabolism in man. Electrons are supplied to the cytochromes by NADPH through the flavoprotein NADPH-cytochrome P450 reductase (CPR)....

Major technological and scientific challenges arise from the pressure to provide widely available and sustainable technologies for the societal requirements for health and a...

There is conflicting information about properties of polycrylic acid and its behaviour in aqueous solution. This proposal for an investigation by SANS that is directed at...

Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly to lead to interfacial adsorption and solution nano-aggregation....

Many formulations comprise distinct chemical species that exhibit antagonistic or synergistic interactions that result in unpredictable behaviour. Previous work from our group...

This proposal constitutes part of our ongoing study towards understanding the solution aggregation of collagen based polypeptides and their interactions with model surfactants....