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TCR alpha and beta repseq
TCR Repertoire sequencing raw reads TCR alpha and beta for several species -
m1A marks translation initiation sites in human and mouse messenger RNA [Sequ...
We developed a novel approach, m1A-seq, for high-resolution mapping of the transcriptome-wide m1A landscape, based on antibody-mediated capture followed by massively parallel... -
Pol II pausing is a milestone on the road to complex animals
PRO-seq experiments in multiple organisms. Also, PRO-seq experiment of Nelfb and Nelfe degron mESC in serum/LIF with or without dTAG-13. Overall design: We used Precision... -
Conservation and divergence of methylation patterning in plants and animals
Cytosine DNA methylation is a heritable epigenetic mark present in many eukaryotic organisms. While DNA methylation likely has a conserved role in gene silencing, the levels and... -
Transcriptome-wide mapping reveals widespread dynamic regulated pseudouridyla...
Pseudouridine is the most abundant modification occurring on RNA, yet with the exception of a few well-studied RNA molecules little is known about the modified positions and... -
Three-layered control of mRNA poly(A) tail synthesis in Saccharomyces cerevisiae
Biogenesis of most eukaryotic mRNAs involves the addition of an untemplated polyadenosine (pA) tail by the cleavage and polyadenylation machinery. The pA tail, and its exact... -
A comparison of evolutionary changes and constraints on gene regulation betwe...
We report time-series transcriptome of developing bamboo shark fin buds and mouse forelimb buds, and open chromatin regions of developing mouse forelimb buds. The major... -
Genome-wide recombination map construction from single individuals using link...
Meiotic recombination rates vary across the genome, often involving localized crossover ”hotspots” and ”coldspots”. Studying the molecular basis and mechanisms underlying this... -
dsRNA-Seq: Identification of viral infection by purifying and sequencing dsRNA
RNA viruses are a major source of emerging and re-emerging infectious diseases around the world. We developed a method to identify RNA viruses that is based on the fact that all... -
Doxorubicin induces double-strand breaks at CpG island promoters
Doxorubicin is a widely used chemotherapeutic drug that intercalates between DNA base-pairs and posions Topoisomerase II, although the mechanistic basis for cell killing remains... -
Mus musculus Homo sapiens Raw sequence reads
Endogenous retroviruses (ERVs) are transposable elements that cause host genome instability and usually play deleterious roles such as tumorigenesis. Recent advances also... -
Evidence against tetrapod-wide digit identities and for a limited frame shift...
In crown group tetrapods, individual digits are homologized in relation to a pentadactyl ground plan. However, testing hypotheses of digit homology is challenging because it is... -
Comparative analysis of epigenomic evolution in mammals
This study used comparative epigenomic data from multiple mammalian species to investigate the roles of DNA methylation in gene evolution, species trait evolution, and genomic... -
Oceanic microplankton do not adhere to the latitudinal diversity gradient
A latitudinal biodiversity gradient has captivated ecologists for years, and has become a widely recognized pattern in biogeography, manifest as an increase in biodiversity from... -
Mus musculus Raw sequence reads
Mouse raw sequence reads -
Mus musculus Raw sequence reads
OP VS Control Mice -
Mus musculus Raw sequence reads
16s rRNA Sequencing Analysis of 30 Mouse Feces -
Virome profiling of an Amur leopard cat reveals multiple anelloviruses and a ...
As a small top predator, Amur leopard cat (Prionailurus bengalensis euptilurus) is widely distributed in Northeast Asia and plays an important role in the control of small... -
Comparative analysis of amplicon and metagenomic sequencing methods reveals k...
Background: The interplay between hosts and their associated microbiome is now recognized as a fundamental basis of the ecology, evolution and development of both players. These... -
Multiplexed? ?profiling? ?facilitates? ?robust? ?m6A? ? quantification? ?at? ...
N6-methyladenosine (m6A) is the most prevalent modification of mRNA in mammals and plays a major role in the post-transcriptional regulation of gene expression. To interrogate...