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Conformational Evaluation of Biodegradable Model Polymer-Drug Conjugates
Previous SANS studies of anti-cancer polymer-drug conjugates (PDCs) (HPMA-Doxorubicin) identified a correlation between conjugate solution conformation and clinical results. The... -
Spin Excitations and "Hourglass" Dispersion in the Model High-Tc superconduct...
The unique "hourglass"-type dispersion observed within several classes of hole-doped cuprates has garnered considerable theoretical and experimental interest. Here we propose to... -
Measurement of Residual Strains/Stresses in Welded Linepipes for Deep-sea Oil...
The demand for deep-sea oil and gas supply is increasing due to the higher demand on energy and security of energy supply. The pipelines for transporting oil and gas are... -
Magnetic Excitations of a Model Quantum Spin Ladder
(C5H12N)2CuBr4 is the best realisation found to date of an antiferromagnetic quantum spin ladder in the strong coupling limit. This system displays an extremely rich phase... -
Head Group charging and anaesthetic Interaction with Model Bilayers
The mechanism of general anaesthetic action is poorly understood despite their widespread use. It is hoped that investigating the interaction of anaesthetics with lipid bilayers... -
Understanding Phospho-L-Serine (PS) role in the Organization of Cholesterol C...
Our goal is to understand the role of POPS, a lipid component only found in the inner leaflet of plasma membrane, in the organization of cholesterol in cell membranes. Our... -
Antimicrobial Peptide Binding & Rearrangement in Model Membranes ¿ Building a...
Antimicrobial peptides (AMPs) are attractive drug candidates because of their selectivity and speed of action against bacteria. We have developed a novel approach to delivering... -
Magnetic Excitations of a Model Quantum Spin Ladder
(C5H12N)2CuBr4 is the best realisation found to date of an antiferromagnetic quantum spin ladder in the strong coupling limit. This system displays an extremely rich phase... -
Neutron Reflectivity Study of Antimicrobial Peptides Interacting with Lipopol...
The outer membrane (OM) of gram negative bacteria is mainly constituted of highly polydisperse and amphiphilic lipopolysaccharide (LPS), an endotoxin which is accompanied by... -
Understanding the Affect of Lipid Tail Saturation on Anaesthetic Interaction ...
The mechanism of general anaesthetic action is poorly understood despite their widespread use. It is hoped that investigating the interaction of anaesthetics with lipid bilayers... -
Model biomembrane dendrimer interactions
The objective of the present study is to investigate the interaction between PAMAM dendrimers and solid supported model biomembranes of high fluidity. These membranes consist of... -
Investigation of a Potential realization of the Nersesyan-Tsvelik Model in (N...
We propose to investigate the highly one-dimensional (1D) S=1/2 Heisenberg antiferromagnet (NO)[Cu(NO3)3] which is a potential realization of the Nersesyan-Tsvelik model. The... -
The interaction of Plant Defensins with Model Lipid Membranes : Understanding...
Plants do not have the sophisticated immunoglobulin immune systems of vertibrates, instead they posses a series of stimuli based responses which defend against pathogentic... -
Effect of Temperature on the Transbilayer Structure of a Model Erythrocyre Me...
In recent years, it has become understood that rather than being homogenous mixtures, biomembranes show a complex phase behaviour, with regions of uniform phases, and others... -
Investigation of a Potential realization of the Nersesyan-Tsvelik Model in (N...
We propose to investigate the highly one-dimensional (1D) S=1/2 Heisenberg antiferromagnet (NO)[Cu(NO3)3] which is a potential realization of the Nersesyan-Tsvelik model. The... -
Copy of: Spin Dynamics of the Central Fe Atom of Reduced Model Fe-Porphyrins
We propose to study the dynamics of the central Fe spin in reduced model Fe-porphyrins. Our aim is to clarify a relatioship between the spin dynamics of Fe and functions of... -
Maps (pdf) and raster images (tif) of predicted rural land cover suitability ...
This study projects land cover probabilities under climate change for corn (maize), soybeans, spring and winter wheat, winter wheat-soybean double cropping, cotton, grassland... -
PREFCLIM: A high-resolution mixed-layer climatology of the eastern tropical A...
PREFCLIM is a mixed-layer climatology for the Eastern Tropical Atlantic. The climatology contains a high-resolution (0.25 degrees) monthly-mean mixed-layer hydrography... -
Simulation of leatherback turtle hatchling dispersion patterns in the Gulf of...
This data set describes the location of virtual floats representing turtle hatchlings throughout 60 modeled years. Floats were constrained to remain within depths of 0-6 m due... -
SHYFEM model results for the Po River-Delta-Sea system, link to NetCDF files
This dataset includes the results of the application of the SHYFEM numerical model to the Po River-Delta-Sea (RDS) system (Italy). The hydrodynamics and the interaction between...