161 datasets found

Several bacterial species have been implicated in the development of colorectal carcinoma (CRC), but CRC-associated changes of fecal microbiota and their potential for cancer...

Human faeces Metagenome

Endogenous retroviruses (ERVs) are transposable elements that cause host genome instability and usually play deleterious roles such as tumorigenesis. Recent advances also...

The connection between evolution of regulatory elements and downstream gene expression is incompletely understood in mammals. We carried out a large-scale comparison of matched...

, we analyzed the clinical outcomes of GC patients with MET and FGFR2 amplification using the next-generation sequencing (NGS) database cohort at Samsung Medical Center, which...

Bacterial and Archaeal community structure in the central Arctic Ocean

As a small top predator, Amur leopard cat (Prionailurus bengalensis euptilurus) is widely distributed in Northeast Asia and plays an important role in the control of small...

Prolonged intervention studies investigating molecular metabolism are necessary for a deeper understanding of dietary effects on health. Healthy men and mice ingested saturated...

Background: The interplay between hosts and their associated microbiome is now recognized as a fundamental basis of the ecology, evolution and development of both players. These...

Here we present genomic data from 5 individuals dating to ca. 3000-2800 BCE from the Dzungarian Basin and 13 individuals dating to ca. 2100-1700 BCE from the Tarim Basin,...

North Atlantic marine snow (oil associated) microbial sequences

Cells are constantly under attack by a plethora of DNA damaging agents that arise from both exogenous and endogenous sources. To deal with this threat to cell and organism...

Here we present genomic data from 5 individuals dating to ca. 3000-2800 BCE from the Dzungarian Basin and 13 individuals dating to ca. 2100-1700 BCE from the Tarim Basin,...

In conclusion, we showed that when patients with metastatic solid cancer receive NGS test, approximately 2.0% have RAF1 aberrations in their tumor specimen. Overall, our data is...

The knowledge of species composition and functional aspects of the human microbiome is steadily increasing, but still limited information regarding its variation on a global...

Background: The development of gut microbiota in infancy is important in the maturation of the immune system. Deviations in colonization patterns have been associated with...

Circular RNAs (circRNAs), a novel class of endogenous RNAs, have been recognized to play important roles in physiology and diseases. However, the molecular mechanisms that...

Recent evidence suggests that repeated antibiotic usage independent from recent consumption lowers microbial diversity and changes the gut microbiota community for a long...

Transfer RNAs (tRNAs) are key adaptor molecules in the protein translation machinery. In order to become fully active, they are heavily modified posttranscriptionally. Inosine...

This study determines that genome skimming, shallow depth of sequencing, is capable of accurately quantifying global DNA methylation level across a range of vertebrates.