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Solution structures of the immunologically important proteins IgA and C3b
We are unravelling the solution structures of the Fab and Fc fragments in the IgA antibody family important in mucosal immunology. Having completed the structures for IgA... -
Effect of alloying on the misfit of Ni-Ni3Al-Ni3V alloys
The exceptional high temperature mechanical properties of Ni-base superalloys has resulted in their widespread use in high temperature applications. These alloys conventionally... -
Solution structures of the immunologically important proteins IgG and C3b
IgG antibody represents one-third of new drugs currently in development. We will unravel the solution structures of the Fab and Fc fragments within IgG. Following our earlier... -
Commissioning PIGLET
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Understanding the structural change of caseinate under mild heat and shear
Producing meat analogue instead of real meat is an effective way to reduce carbon emission and improve animal welfare. Calcium caseinate is a prominent candidate for making a... -
SANS studies of the micellar structures of mixtures of lauroyl-L-carnitine an...
As a new group of synthetic biosurfactants, the acyl-L-carnitines offer potential for different applications including working as edible biocides. Whilst extensive studies have... -
Investigating the structure of novel chloride-containing bioactive glasses fo...
A range of novel chlorine-containing bioactive glasses have recently been developed at Queen Mary University of London for dental and orthopaedic applications. At present little... -
Solution structures of the immunologically important proteins IgA, C3 and IgG
Abnormally glycosylated IgA leads to IgA nephropathy, the most common cause of renal failure. IgG antibody represents one-third of new drugs currently in development, and its... -
Effect of End Group on RAFT-Polymers for Lipid Nanodisc Stabilisation
Polymer stabilized lipid nanodiscs offer enormous potential as tools for enabling membrane protein structural studies & biophysics. Previously we studied discs formed using... -
SANS Study of the interaction of reconstituted model wheat waxes with non-ion...
The understanding of the plant wax-surfactant interaction process is crucial to the development of more effective pesticide and fungicide formulations, essential for improving... -
Potteries from the Sumerians city of Abu Tbeirah (Iraq). A non desctructive s...
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The effect of confinement on the structure of alcohol-water mixtures
Compared with gas phase reactions, liquid phase catalytic processes are complex due to the effect of the solvent. The solvent controls many aspects of the overall reaction... -
Drug solvation in amphiphilic solutions: understanding how small molecules cr...
Understanding how drugs interact with physiologically relevant environments is crucial for the future of effective drug design. An important class of potential drugs are central... -
Morphology and Phase Diagram of Thermoresponsive Polymer-Protein Conjugates
Using an enzyme mediated conjugation method we have prepared well-designed protein-polymer conjugates using a model protein, green fluorescent protein (GFP) with... -
Investigation of phosphatidylcholine and its interaction with 1,2 propandiol ...
The aim of the present study is to use neutron diffraction enhanced with isotopic substitution and subsequent computer simulations to determine the head group solvation of a...
