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Study of Small molecule effects on AB interactions with model lipid layer by ...
Neutron reflectometery will be used to provide the vital information about the interaction/conformation of the organophosphonate compound on the lipid structure in the... -
Purothionin binding to model fungal lipid membranes
Purothionins and defensins are basic, amphiphilic, cysteine-rich and low molecular weight plant defence proteins. These proteins are active against a broad range of... -
Neutron reflection from the surface of a liquid 3He-4He mixture
In our previous experiments we have investigated the surface properties of liquid 3He - 4He mixtures by neutron reflection. We have shown that in broad temperature range there... -
Interaction of amino acid based biosurfactants with model lipid bilayers
N-acyl amino acids are surfactants with attractive applications in different technological fields. They are referred to as mild surfactants because they are commonly considered... -
Effect of calcium ions and ionic strength on model bilayer structure
Calcium ions have been shown in a preliminary experiment to have a dramatic effect on the thickness and structure of free supported bilayer films. In this proposal we... -
Nature of the protein corona on nanoparticle surfaces
When nanoparticles enter a biosytem they rapidly acquire a protein corona. The nature of the outer part of this corona will determine the response of the biosystem to the... -
Dye...TiO2 interfacial structure of working electrodes in dye-sensitized sola...
The transparent and low-cost nature of dye-sensitised solar cells (DSCs) affords them niche prospects for electricity-generating windows in buildings for energy-sustainable... -
Interfacial properties of a lung protein after exposure to gas-phase ozone
Lung surfactant protein B, SP-B, is found at the air-water interface of the lung. A deficiency in SP-B at birth is known to be fatal. We have recently successfully studied the... -
Structural studies of thermo-responsive nanogels at the oil-water interface
Nanogels because of their three-dimensional physical structure and tunable chemical properties as well as their stimuli-responsive nature have emerged as one of the most... -
Mixed H/F-Carbon surfactant monolayers for fire-fighting applications
The aim is to use Neutron Reflectivity (NR) to gain essential information on the adsorption properties of fluorocarbon/ hydrocarbon mixtures in commercial fire-fighting foam... -
Wetting Transitions of Tackifiers in Adhesives
Migration and surface segregation of low molecular weight oligomers in adhesive formulations is a poorly understood, but hugely important phenomenon, responsible for most of the... -
Spin-polarized electron states at the interface of EuO and 3d transition meta...
The objective of this experiment is the study and characterization of spin-polarized electron states at the interface of EuO and 3d transition metal oxides. EuO is a... -
calcite water interface
The interface of CaCO3 (calcite) and water is of paramount importance in a number of key academic and industrial areas, including scale deposition in domestic and industrial... -
Interfacial conformation of antibody and antigen binding capacity
Antibody-antigen binding has been extensively used in many technological applications such as immunoassays, chemical analysis and bionanotechnology. The crucial element... -
Influence of Aliphatic for Tackifiers on Glassy Domains in Hot Melt Adhesives
We have recently shown by neutron reflectometry, that the glassy styrenic blocks, normally assumed to be impervious to aliphatic oligomers do in fact show a significant level of... -
Amyloid β peptide and α-synuclein association at lipidmodel membranes
We plan to investigate the interaction between amyloid proteins and model biomembranes deposited on solid surfaces. The model membranes will be single zwitterionic and mixed... -
Binding behaviour of PAMAMs G5 and G4.5 to zwitterionic and anionic lipid bil...
Polymers are commonly used in drug delivery to create dosage forms that enable delivery of the active ingredient to the site of action within the body. Towards controlled drug... -
Templating of titania films in cationic-anionic surfactant polymer solutions
In this proposal we wish to continue our recent work using polyelectrolyte-surfactant films as templates for inorganic structures, in this case titania.... -
In situ study of destruction of a denatured surface protein by protease (Savi...
New detergents will increasingly rely on sustainable products and the use of enzymes will become ever more important. However, the process of destruction of stains (often... -
Acid /amine complexation on an iron oxide /Oil interface
This experiment seeks to characterise the monolayer composition and structure of binary mixtures of fatty acid and amine. This represents a key additive system used commercially...
