Oxygen isotope measurements have been made in foraminifera from over 60 deep-sea sediment cores. Taken together with the oxygen isotope measurements published by Emiliani from Caribbean and Equatorial Atlantic cores, this comprises a unique body of stratigraphic data covering most of the important areas of calcareous sediment over the whole world ocean. The oxygen isotopic composition of foraminifera from cores of Late Pleistocene sediment varies in a similar manner in nearly all areas; the variations reflect changes in the oxygen isotopic composition of the ocean. The oceans are mixed in about 1 ka so that ocean isotopic changes, resulting from fluctuations in the quantity of ice stored on the continents, must have occurred almost synchronously in all regions. Thus the oxygen isotope record provides an excellent means of stratigraphic correlation. Cores accumulated at rates of over about 5 cm/ka provide records of oxygen isotopic composition change that are almost unaffected by post-depositional mixing of the sediment. Thus they preserve a detailed record of the advance and retreat of the ice masses in the northern hemisphere, and provide a unique source of information for the study of ice-sheet dynamics.