The Amazon and Pará Rivers make up the largest and 5th largest rivers on earth, respectively, and converge in the Amazon-Pará Estuary. Prior to this dataset however, sparse trace metal data from this region were available. A GEOTRACES process study (GAPr11; cruise M147) was conducted on the RV Meteor during a period of high river discharge to study the flux and cycling of trace metals in this globally important region. Samples for dissolved (<0.2 µm) trace metals (Al, Mn, Fe, Co, Ni, Cu, Zn, Cd, Pb) and Ra-228 were collected in the Amazon and Pará River estuary in April-May 2018. Using these data, we determined the flux and estuarine removal of trace metals from the Amazon and Pará Rivers into the Atlantic Ocean.