Characterisation of a sponge microbiome using an integrative genome-centric approach

Marine sponges often host diverse and species-specific communities of microorganisms that are critical for host health. Previous functional genomic investigations of the sponge microbiome have focused primarily on specific symbiont lineages, which frequently make up only a small fraction of the overall community. Here we undertook genome-centric analysis of the symbiont community in the model species Ircinia ramosa and analysed 259 unique, high quality metagenome-assembled genomes (MAGs) that comprised 74% of the I. ramosa microbiome. Addition of these MAGs to genome trees containing all publicly available microbial sponge symbionts increased phylogenetic diversity by 32% within the Archaea and 41% within the Bacteria. Metabolic reconstruction of the MAGs showed extensive redundancy across taxa for pathways involved in carbon fixation, B-vitamin synthesis, taurine metabolism, sulfite oxidation, and most steps of nitrogen metabolism.

Identifier
Source https://data.blue-cloud.org/search-details?step=~012C74E025DDC3D244428B8344FAEDC7E5BE373812C
Metadata Access https://data.blue-cloud.org/api/collections/C74E025DDC3D244428B8344FAEDC7E5BE373812C
Provenance
Instrument NextSeq 500; ILLUMINA
Publisher Blue-Cloud Data Discovery & Access service; ELIXIR-ENA
Publication Year 2024
OpenAccess true
Contact blue-cloud-support(at)maris.nl
Representation
Discipline Marine Science
Spatial Coverage (147.380W, -18.490S, 147.380E, -18.490N)
Temporal Point 2016-10-01T00:00:00Z