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Component Structural Characterization
NDA Agreement No. 1011-169 Lubrizol No. 36695 -
SANS contrast measurements on important protein/DNA interactions from RCaH
This proposal is to perform SANS contrast measurements on three protein/DNA interactions currently worked on at the Research Complex at Harwell. This is part of an ongoing... -
Static and dynamic structure of oil/water microemulsions to improve enhanced ...
After initial and secondary oil recovery up to 50% of the oil can be left behind in the reservoir. Various enhanced oil recovery (EOR) techniques can be applied to improve the... -
Temperature driven self-assembly of amphiphilic block copolymers in water.
Amphiphilic copolymers with perfluoroalkyl blocks provide self-assembled nanostructures, in water, via the association and/or self-folding of the copolymer chains. This feature... -
Solubilisation in Zwitterionic Micelles: Effect of Structure
The project aims to probe the relationship between surfactant structure, the micelles formed in solution, and the type of drug molecules that the micelles solubilise. Once... -
Structural and mechanistic study of nanocapsule / hydrogel composites for dru...
The targeted delivery of non-water soluble drugs for applications such as cancer remains a major challenge. Nanocapsules are new materials that can act as a depot for such drugs... -
Aggregation behaviour of aqueous hairy rod conjugated polyelectrolyte/surfact...
Small angle neutron scattering (SANS) will be used to characterise the structures of aggregates formed between the anionic conjugated polyelectrolyte... -
Responsive polymer brushes grafted from gold nanoparticles: interaction with ...
We will use SANS to characterize dispersions of gold nanoparticles functionalized with poly(dimethyl aminoethyl methacrylate) brushes grafted from 25 nm gold nanoparticle... -
The mode of action of a novel disruptive antimicrobial technology on model me...
A Unilever proprietary technology has been shown to inhibit biofilm growth and development, and is also found to possess antimicrobial activity, effective both as a... -
Effect of shear and charged polymers on cellulose microfibrils
Cellulose is an important natural material used in many industrial applications, such as food and medicine. Cellulose micro-fibrils (CMF) are produced from wood, plants, and... -
SANS studies of mixed phsopholipid:sterol vesicles and their interaction with...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
Structure and mobility of surfactant additives in PDMS resin
Polysiloxane materials are commonly used in marine coatings due to their inherently low surface energy and flexibility which makes them suitable base materials for foul release... -
Temperature-dependent structural behaviour of the collapse transition of high...
We shall use small angle neutron scattering to investigate the structural behaviour of the temperature sensitive highly branched poly(N-isopropyl acrylamide) [PNIPAM]. These... -
On the structure and composition of non-lamellar lipid-based liquid crystalli...
Liquid crystalline particles consisting of glycerol dioleate (GDO) / soy phosphatidylcholine (SPC) mixture and stabilised by polysorbate 80 (P80) have proven to be suitable as... -
SANS study of interaction of iron with alginate
Bowel cancer is the fourth most common cancer in the UK with approximately 41,000 individuals in the UK diagnosed annually. Importantly it is estimated that over half of all... -
Contrast matching of selectively deuterated glycerides for scattering studies...
Lipid nanoparticles (LNPs) can be formed from glycerides and loaded with diverse cargo for healthcare applications. A key advantage of LNPs over liposomes is the significant... -
Unlocking Structure-Property Relationships in Composite Semiconducting Nanopa...
Colloidal dispersions of organic semiconducting nanoparticles (NPs) have shown promise for the generation of active layers in organic solar cells.Composite NPs containing a... -
Study of creep cavitation in pre-strained creep hourglass test specimens
Studies of creep behaviour in structures that operate at elevated temperatures such as nuclear power plants are important for structural integrity assessments. The effect of... -
Aggregation in ionic liquids
The aim of this experiment is to investigate surfactant aggregation in ionic liquids and also ionic liquid ¿ oil and ionic liquid ¿ water microemulsions via SANS. Contrast... -
The structure of nanographene and nanographite intercalates in solution
We aim use SANS to study in situ structure of solutions of uncharged and charged graphene formed by dissolving graphite and graphite intercalation compounds. We wish to compare...
