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The membrane lipid composition regulates the orientation of Tissue Factor ext...
Tissue Factor (TF) is a membrane protein located on the cell surfaces of extravascular cells. TF activity is fundamental for normal homeostasis- the physiological process which... -
Di-chain sulfobetaine monolayers at the air-solution interface
Here we wish to continue our investigation of sulfobetaine surfactants in which the charges on the zwitterionic headgroup are reversed compared to those on zwitterionic... -
Composition of model binary surfactant mixtures at the solid/liquid interface
The adsorption at the silica water (both hydrophilic) interface of anionics can be induced by the addition of non ionics, the degree of which provides information on the surface... -
Probing the structure/function relationship of NhaA protein incorporated into...
We propose to perform combined measurements of neutron reflectometry (NR) and impedance spectroscopy (IS) to investigate the structure/function relationship of tethered bilayer... -
Effect of Cholesterol on NHE1 intracellular domain adsorption on lipid bilayers
The Na+/H+ exchanger isoform 1 (NHE1) is a transmembrane protein with the primary function of regulating the pH in the cytosol by exchanging one proton with one Na+ ion. The... -
Adsorption of bioengineered antibodies at the oil/water interface
Following our previous study of adsorption of Fc, Fab and the constituent mAb COE-3, we continue to explore how two bioengineered mAbs adsorb at the oil/water interface by... -
Model anionic/non ionic surfactant adsoption at the interface below room temp...
An experiment performed on INTER last year found extreme non ideal mixing between C12E8/SLES3 at the air water interface: this feature became more extreme as the temperature... -
Magnetic Proximity Effects in Ferromagnetic-Superconducting Spin Valves
The recent experimental verification of the unique odd-frequency spin triplet superconductivity in artificial thin film ferromagnetic-superconducting structures is likely to... -
Probing the interfacial wetting of superhydrophobic, lithographically pattern...
Phenomena surrounding the wetting of natural or artificial topographically patterned surfaces are found systems associated with the diverse fields of chemical engineering,... -
Scaling Model for the adsorption of macromolecules at the oil-water interface
The aim of this proposal is the application of the scaling model for the adsorption of proteins at the oil-water interface. The adsorbed amount for a series of oils as a... -
Charged nanogels and their ability to penetrate model lipid membranes
Drug delivery through the skin is an important route for administration of therapeutic agents. However, the outermost layer of the skin, the stratum corneum provides a... -
Interfacial structure in self-assembling conjugated polymer photovoltaic devices
The proposal aims to determine the degree of interfacial mixing and roughness at an interface between two conjugated polymers, as part of a broder program to understand how to... -
Stabilization of anisotropic pigment particles: Reflectivity
We wish to determine the effect of various stabilisers on anisotropic pigment particles that are being developed for use in liquid crystal composites. We will investigate the... -
Layered Structure of Doped Organic Films for OLEDs
Conjugated organic semiconductors form an exciting class of materials that can be used in a variety of cutting edge technologies including organic light-emitting diodes (OLEDs),... -
Interaction between superconductivity and magnetism in iron-lead thin films
A previous CRISP measurement allows us to show for the first time using PNR a change in the response due to superconductivity in an Fe/Pb/Fe tri-layer sample. This type of... -
Surface adsorption of lipopeptides: interfacial layer structure
Lipopeptide surfactants are highly effective at reducing interfacial tension. However, there is a general lack of understanding of the relationship between their molecular... -
Structural studies of surfactants at the metal-aqueous interface
This proposal relates to the structural studies of cationic surfactant adsorption on an iron oxide metal surface. The driving force for the adsorption of cationic surfactants to... -
Membrane interactions of a viral scission protein
Influenza virus is a pathogen of great medical importance that causes seasonal epidemics and sporadic pandemics. Among the least understood events of the influenza virus... -
Electric field effect on the interfacial uncompensated spins in the Co/BiFeO3...
We propose a study on the electric field control of uncompensated spins in the Co/BiFeO3/STO bilayer system by PNR. Multiferroic BiFeO3 (BFO) has attracted enormous interest... -
Developing a generic gravimetric method to determine the composition of films...
We propose to develop a new and generic, multi-probe technique to characterize the mass, and changes in mass, of material probed in a NR experiment. This methodology will be...
