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Protein-decorated superparamagnetic iron oxide nanoparticles
The aim of this research is to understand the structural confirmation of dextran coated iron oxide (Fe3O4) nanoparticles in the presence of Bovine serum albumin (BSA) in aqueous... -
Contrast Variation Experiments for Probing the Structure of Pickering Nanoemu...
Polymerisation-induced self-assembly is an efficient and versatile method of producing functional block copolymer spheres, worms and vesicles in a range of media (e.g. water,... -
Nanosuspsomicroemulsions: nanosuspension stabilty
At Kings College London we have recently developed a novel combination formulation, a nanosuspsomicroemulsion (NSME), comprising of a microemulsion (ME) containing one drug and... -
Temperature and flow stability of model sodium alkylbenzene sulfonate (NaLAS)...
Linear sodium alkylbenzene sulfonate (NaLAS) is one of the most extensively used anionic surfactant in the world, mainly as a biodegradable laundry detergent, with an annual... -
Structural origin of anomalous relaxation behaviour in alcohol-water mixtures
In recent dielectric and calorimetric studies of some alcohol-water mixtures we have discovered unexpected and unexplained relaxation behaviours. Our aim with this proposal is... -
The effect of alcohol chain length on the interaction between PS-PEO copolyme...
In many applications, surfactants are formulated with a variety of additives to achieve a desired range of properties; polymers and cosurfactants/cosolvents (such as alcohols)... -
Cucurbituril HostGuest Micellar Systems: Structure and Self-Assembly
One of the grand challenges in the physical sciences is fabricating materials with a defect-free controlled structure on the submicron scale. Realisation of this challenge will... -
Structure of Cellulose Nanofibril Gels
This proposal is part of a new project based on understanding the formation of gels in suspensions of partially oxidised cellulose nanofibrils with small amounts of salt or... -
SANS studies of phospholipid:sterol vesicles and the membrane interactions of...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
Small-Angle Neutron Scattering studies of a bacterial colonization factor
We plan to carry out SANS experiments on a bacterial colonization factor to elucidate how it interacts with chitin, which is found on the surface of plankton and crustaceans.... -
Effect of surfactant head group on micelle structure of drug containing micelles
The aim of the current project is to probe (at the nanometer length scale) the relationship between the solution structures of a surfactant molecule, the aggregate(s) it forms... -
Surfactant induced gelation of TEMPO-oxidized cellulose; Using betaine-based ...
Our group has been working cellulose nanofibrils (OCNF) which form hydrogels in the presence of certain additives. Previously, we have studied the effect of salt, single... -
Structure of alkylated aza-crown ether inverse micelles
Ion transfer through fluid-fluid interfaces plays decisive roles in many natural and industrial processes. In studies of Cu(II) transport by Permeation Liquid Membrane (PLM)... -
SANS study of hollow nanoparticles and their solvent release
Hollow nanoparticles (HNP) have been successfully used for encapsulation and controlled release of biochemicals such as drugs, DNA, and dyes. However no in-situ method has been... -
Dynamics of amyloid protein fibril growth using isotope-labelled SANS
This proposal aims use a novel approach whereby deuterated amyloid peptide fibrils are givenhydrogenated growing ends, and analysed using SANS. The data will enable us to... -
Using SANS2D to resolve the opening of MscL clusters in proteoliposomes in re...
In bacteria, mechanosensitive ion channels such as MscL protect cells against osmotic shock. Although crucial for protecting cells, as with all ion channels, they have the... -
SANS studies of mixed phospholipid:sterol vesicles and their interaction with...
The increasing incidence of pathogenic fungi resistant to treatment with amphotericin B (AmB) has created a demand for novel anti-fungal agents that can circumvent the... -
Co-assembly of gold nanoparticles with wormlike micelles
Gold nanoparticles (GNPs) are attracting tremendous interest in nanotechnology due to their plasmonic properties, in particular the localized surface plasmon resonance effect... -
Encapsulation of Non-Steroidal Anti-Inflammatory Drugs Using Novel Pluronic G...
The research topic is encapsulation of a hydrophobic drug, flurbiprofen, using novel amphiphilic graft copolymers (AGCs). The AGCs of interest are shown in Figure 1: Preliminary... -
Binary colloidal mixtures - SANS contrast variation to study high concentrati...
Mixtures of colloidal particles of essentially two different sizes are commonly used in technological applications such as film formation on surfaces, paper coatings, etc....