318 datasets found

The negative effects of exposure to ultraviolet rays, 290-400 nm, are well known. Long exposures to these rays often cause skin damage (e.g. skin burns, melanoma). Topical...

Staphylococcus aureus is a normal skin commensal and an opportunistic pathogen that presents serious threat to healthcare. It is the causative agent of septicaemia and...

This proposal is part of a project based on understanding the formation of gels in suspensions of partially oxidised cellulose nanofibrils and small amounts of additives, such...

Cyclic peptides with alternating side chain stereochemistry are capable of self-assembling into long nanotubes. The conjugation of polymers to these peptides renders the...

This proposal aims to explore a cheaper and more environmental-benign surfactant system for yielding efficient water/CO2 microemulsions. The new surfactants permit high...

Oils are commonly used in personal care industry as emollients. Owing to their undesirable feel they are formulated in oil in water emulsions form. Emulsions contains...

Liquid pharmaceutical formulations are commonly comprised of proteins and surfactants, which interact in solution in order to provide an increase in system stability. Although...

The MES is representative of a promising group of anionic surfactants which have the potential for improved performance and biocompatibility / biosustainability, and their...

Soft self-assembled structures have been extensively used as drug nanocarriers. Their building blocks, naturally occurring and synthetic amphiphiles (lipids or block...

This proposal constitutes part of our ongoing study towards understanding the solution aggregation of collagen based polypeptides and their interactions with model surfactants....

The microscopic dynamics of associative polymers that self-assemble into micellar structures play a key role for their macroscopical properties, with important implications for...

The glycosylation of glycoproteins is a major determinant of their stability, and glycans also affect their aggregatibility (precipitation). An understanding of this is...

Many formulations comprise distinct chemical species that exhibit antagonistic or synergistic interactions that result in unpredictable behaviour. Previous work from our group...

The study of antifungal and antibacterial action is of great interest and there are still many unknowns concerning the action of membrane lytic materials, and the way that...

It is difficult for the naked external gene to become internalized due to its similar charge to the extracellular membrane surface. Various cationic copolymers and cationic...

In the proposed experiments we extend previous work on characterization of aggregates formed by cationic conjugated polymers and oligomers in water. Particular emphasis will be...

This proposal is part of a broad collaboration between Oxford, CCLRC, and Unilever in the study of surfactants and mixed surfactants at interfaces and in solution. This is an...

Ultrasound is a very attractive and patient-friendly imaging technique, as it is easy to use, fast and non-invasive. Nevertheless, its use is severely limited by the low...

Short peptide sequences consisting of hydrophobic and hydrophilic amino acid units are capable of self-assembly to lead to interfacial adsorption and solution nano-aggregation....

We have synthesised alkyl phosphorylcholine (CnPC) surfactants in hydrogenated and deuterated form and have determined their solution aggregation using SANS. In this part of...