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Molecular Mechanistic Processes of Complexation between DNA and Cationic Copo...
It is difficult for the naked external gene to become internalized due to its similar charge to the extracellular membrane surface. Various cationic copolymers and cationic... -
Molecular Mechanistic Processes of Complexation between DNA and Cationic Copo...
We have previously used LOQ to identify the complex (polyplex) structures formed between a short single strand DNA and a cationic diblock copolymer MPC30-DEA60. The SANS... -
Solubilisation of Drug Molecules in Nonionic Surfactant Micelles: Structural ...
This proposal aims to understand how the structure of non-ionic surfactant micelles affects the amount of fungicides solubilised. SANS is a technique unique for unravelling the... -
Impact of Stereochemistry and Diamine Structure on Absorption of Constructed ...
Chiral gemini surfactants containing stereogenic centers and two amphiphilic moieties, not only maintain the chiral properties, but also exhibit stronger aggregation properties,... -
Influence of Zn and Ca on the local structure of silico-aluminate glasses
Glasses used as glazes for ceramic bodies will be studied as a function of their composition, with emphasis on two elements, such as Ca and Zn, that show the largest influence... -
Can photo-MuSR method measure carrier recombination lifetime in direct gap se...
In the past years we have developed a method measuring carrier recombination lifetime in semiconductors using the photo-MuSR setup in HIFI. These studies have focused on... -
Use of nitric oxide radicals for the formation of a supramolecular hydrogel
The aim of this proposal is to study the structure of hydrogel systems formed from fluorenylmethyloxycarbonyl (FMOC) protected peptides, via the use of nitric oxide radicals.... -
Neutron diffraction to monitor the state of a non-stoichiometric solid employ...
An unmixed reaction is a dynamic process in which e.g. a metal oxide (which acts as an oxygen-carrier material) is used to e.g. provide oxygen for a reaction during which the... -
OSTEOMETRICS IN BURNED HUMAN SKELETAL REMAINS: ESTIMATING HEAT-INDUCED DIMENS...
This study aims at developing a reliable method for probing diagenetic alterations in human bones upon burning events, by INS spectroscopy. The results will be coupled to Raman... -
Tuning micellar interfacial curvature in CO2 by small molecule additives
This proposal aims to explore co-surfactants, as additives with CO2-active surfactants, for elongating reversed micelles in dense CO2 by using high-pressure small-angle neutron... -
Self-assembly of polymer-stabilised cyclopeptide nanotubes
SANS will be used to determine the structure of nanotube dispersions formed by H-bond stacking of cyclopeptides coated with a sheath of stabilizing polymer. Cyclopeptide... -
The Orientation and Conformation of an Enantiomeric Pair of 310 Helical Pepti...
We wish to investigate the interactions between peptide mimics of peptaibols, a highly active class of natural antimicrobial peptide, and membranes. In particular we are... -
Effect of polar solvent on the structure of monolayers of phospholipid
It is the aim of the proposal is to perform neutron reflectivity (NR) studies combined with contrast variation to determine the structure of phospholipid monolayers on a... -
Solution structure of polyaromatic hydrocarbons
This dataset has no description
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The Effect of Sorbate-Framework Interactions on Controlled Drug Release by Ze...
To understand the controlled release of drug molecules from zeolite hosts, we propose to study using INS the interactions of beta-blocker atenolol with the Brønsted acid sites... -
Effect of Cholesterol on NHE1 intracellular domain adsorption on lipid bilayers
The Na+/H+ exchanger isoform 1 (NHE1) is a transmembrane protein with the primary function of regulating the pH in the cytosol by exchanging one proton with one Na+ ion. The... -
Crystal structure and thermal expansion of acetylene (C2D2)
Acetylene is produced in great abundance in the solar system wherever carbonaceous solids are exposed to energetic radiation. It has been the subject of several studies,... -
The membrane lipid composition regulates the orientation of Tissue Factor ext...
Tissue Factor (TF) is a membrane protein located on the cell surfaces of extravascular cells. TF activity is fundamental for normal homeostasis- the physiological process which... -
The structure of ammonia borane in water, DMSO and THF
There is an increasing urgency to find stable and lightweight hydrogen storage materials for clean transport applications. Promising options being investigated include Mg-based... -
Neutron scattering to characterise protein interactions with solid-liquid int...
Objectives of this proposal aim to shed light on how adsorption processes such as protein A chromatography, used to purify biologics, affect protein propensity for aggregation....