124 datasets found

This proposal is part of a funded (CASE) project, aimed at understanding the delivery of benefit actives (perfumes) to interfaces and the development of new self-assembled...

Hydrophobins are secreted fungal proteins in the form of small lipopetide biosurfactants. They are strongly surface active and self-assemble at interfaces and in solution. This...

Clarithromycin and Levofloxacin are essential antibiotics used to treat bacterial infections such as tuberculosis and pneumonia. Lung surfactants may be used as drug carrier of...

We have recently discovered that above 2 GPa in the liquid/fluid forms water and methanebecome miscible in proportions up to 33 mole% of methane. This proposal is for time to...

This proposal aims to understand how the structure of non-ionic surfactant micelles affects the amount of fungicides solubilised. SANS is a technique unique for unravelling the...

New detergents will increasingly rely on sustainable products and the use of enzymes will become ever more important. However, the process of destruction of stains (often...

THE ROLE OF WATER MOLECULES IN THE ORDERING OF HETEROMETAL ORGANOMETALLIC-POLYMER CHAINS.

We are developing a new protocol for the preparation of lipid bilayers suitable to host membrane proteins with control on their orientation. Our proposed strategy is based on...

We have been developing hydroxypropylmethyl cellulose (HPMC) microspheres for delivering poorly water-soluble drugs. The in vitro dissolution data showed that the presence of...

The interface of CaCO3 (calcite) and water is of paramount importance in a number of key academic and industrial areas, including scale deposition in domestic and industrial...

In a recent EPSRC / Unilever / Oxford CASE project we have used NR to explore and develop optimised delivery mechanism for active benefit agents such as perfumes. In particular...

When nanoparticles enter a biosytem they rapidly acquire a protein corona. The nature of the outer part of this corona will determine the response of the biosystem to the...

The spontaneous formation of multilayer structures at interfaces from surfactant self-assembly has until recently been rarely observed. However, surface multilayer structures...

We propose to use the new SANS2d to study the dynamic structural evolution in the couse of the formation of DNA-cationic polymer complexes. The dynamic process and the mixing...

Calcium ions have been shown in a preliminary experiment to have a dramatic effect on the thickness and structure of free supported bilayer films. In this proposal we...

Neutron reflectometery will be used to provide the vital information about the interaction/conformation of the organophosphonate compound on the lipid structure in the...

The acyl-L-carnitines are a group of novel surfactants. Following our recent home laboratory work to synthesize, purify and characterize them, the aim of this proposal is to...

The aim is to establish the nature of the surface layer of 8CB at the nematic-air interface by measuring neutron reflection from the n=8, 10 and 12 homologues of the nCB series...

Our aim is to examine the structures of disordered gel precursors to nanoporous zeolites that are formed in the early stages of hydrothermal reactions. They are considered to be...

The information gained in the study will be invaluable in aiding our understanding of the structure and transport properties of the cell membrane as well as helping in the...